ASIA case after injection of liquid silicone

Libardi, Camila Secco; Diniz, Lúcia Martins; Musso, Carlos Guido; Badaró, Bruna Anjos

doi:10.1016/j.abd.2019.12.006

Cited by 2 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our patient developed the typical ASIA symptoms at a later point of the disease course. Other cases with late-onset classical ASIA syndrome were previously reported [28,29].…”

Section: Discussionmentioning

confidence: 97%

Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human

2021

View full text Add to dashboard Cite

Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA; Shoenfeld’s syndrome) comprehends a group of autoimmune conditions that flourish in genetically predisposed individuals, following an external stimulus by the so-called adjuvants. Many adjuvants were described, such as vaccines, aluminum and other metals, silicone, tattoos, among others. Those conditions entail defined diseases, such as sarcoidosis and Sjogren’s syndrome, and generalized complex symptoms, for example, fatigue, sleep disturbance, orthostatic intolerance, and other dysautonomic manifestations. Those complaints were previously associated with autoantibodies against nervous system autonomic receptors, especially antibeta 1 adrenergic receptor antibodies, suggesting the autoimmune component of the condition. Here we report on a case of an 18-year-old woman who presented with extreme cachexia due to severe dysautonomia caused by the ASIA syndrome induced by the tetanus, diphtheria, and pertussis vaccine (Tdap).

show abstract

“…Our patient developed the typical ASIA symptoms at a later point of the disease course. Other cases with late-onset classical ASIA syndrome were previously reported [28,29].…”

Section: Discussionmentioning

confidence: 97%

Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human

2021

View full text Add to dashboard Cite

show abstract

Outcomes and Complications of Surgical Removal of Foreign Body Granulomas Due to Illicit Polymer Injection for Cosmetic Purposes

López-Mendoza

Moran-Romero

Mouneu

2021

Aesthetic Surgery Journal

View full text Add to dashboard Cite

Background There are several local complications associated with subcutaneous injection of illicit polymers, including: injection-site deformity, granulomas, and skin changes. Objectives To compare the postoperative complications and symptom flare in patients undergoing surgical excision of foreign-body granulomas. Methods We retrospectively examined data of patients who underwent surgical removal of foreign-body granulomas caused by polymer injection for cosmetic purposes with UAL, en bloc excision with primary closure, skin grafts, or free flaps during 2014–2020. Data collected included demographic and operative parameters. Postoperative complications, symptom flare, and time to flare were reported. Relationship between type of surgery and complications, symptom flare, and time to flare was determined through statistical analysis. Results The final cohort included 49 surgeries (42 primary and 7 secondary) in 35 patients. Overall complication rate was 28.9%, with no significant intergroup differences (30.8%, 20%, 66.7%, and 40%; p = 0.328). Wound dehiscence and skin burns were the main complications. An overall symptom flare of 35.1% in surgical treated areas over a mean period of 28.49 months was reported. Chi-squared test indicated statistical significance between type of surgery and symptom flare (p = 0.004) and between complications and flare (p = 0.013). Kaplan–Meier test for flare was statistically significant (p = 0.006) after comparison of the four groups. Conclusions Rate of postoperative complications was similar for each type of surgery. However, en bloc excision and reconstruction by either primary closure or free flap was associated with a significantly decreased rate of symptom flare and a longer symptom-free period.

show abstract

ASIA case after injection of liquid silicone

Cited by 2 publications

References 5 publications

Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human

Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human

Outcomes and Complications of Surgical Removal of Foreign Body Granulomas Due to Illicit Polymer Injection for Cosmetic Purposes

Contact Info

Product

Resources

About