Beware of reflectance confocal microscopy artifacts when searching hyphae in acral skin

Cinotti, Élisa; Perrot, Jean; Rubegni, Pietro

doi:10.1016/j.abd.2019.04.013

Cited by 2 publications

(6 citation statements)

References 3 publications

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“…All patients were examined by a professional dermatologist (an attending physician with more than five years of professional training) using the Vivascope 1500 RCM device (Lucid Inc, Rochester, NY, USA) [17]. Patients took appropriate postures and fully exposed skin lesions area in resting state, the dermatologist selected the fresh skin lesion with a few scales as inspection area.…”

Section: Rcm Imagingmentioning

confidence: 99%

The challenge of Diagnosing Common Dermatomycosis by Reflectance Confocal Microscopy

Lu¹,

Zeng²,

Zhang³

et al. 2021

JDD

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Background: Traditional detection of fungal infections of the skin relies on microscopy techniques or fungal culture. Currently, reﬂectance confocal microscopy (RCM) has been widely applied to assist the diagnosis of commondermatomycosis with advantages of non-invasiveness, celerity, real time, and repeatability. Materials and Methods: A total of 478 clinically suspected dermatomycosis patients were enrolled in this study including 148 cases of tinea manus and pedis, 188 cases of tinea corporis and cruris and 142 cases of pityriasis versicolor. RCM examination was performed to image the lesions. Aim: This study aimed to summarize the image characteristics of in vivo RCM examination on common dermatomycosis and retrospectively evaluate its accuracy as compared with microscopy results. Furthermore, we attempted to tackle the challenges of RCM diagnosis on common dermatomycosis. Results: Based on RCM images, 231 of 478 (48.3%) patients were detected with hyphae. Among all RCM confirmed cases, 58 out of 148 (39.2%) were tinea manus and pedis, 145 out of 188 (77.1%) were tinea corporis and cruris, and 28 out of 142 (19.7%) were pityriasis versicolor. The remaining patients (51.7%) could not be diagnosed by the dermatologist according to RCM. Hyphae structures were primarily identified during diagnoses of dermatomycosis by RCM. Conclusions: RCM is a novel optical imaging technique that confers high-resolution images of fungi. RCM has certain advantages in the diagnosis of tinea manus and pedis. RCM is not suitable for the diagnosis of pityriasis versicolor.

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Section: Rcm Imagingmentioning

confidence: 99%

The challenge of Diagnosing Common Dermatomycosis by Reflectance Confocal Microscopy

Lu¹,

Zeng²,

Zhang³

et al. 2021

JDD

View full text Add to dashboard Cite

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“…It occurs mainly in coastal areas of countries with tropical and subtropical climates. [1][2][3][4][5][6] Uncommon in Europe, it has been correlated with intercontinental travel and immigration. [1][2][3][4][5][6] According to the TN review only three cases were reported in Italy.…”

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confidence: 99%

“…[1][2][3][4][5][6] Uncommon in Europe, it has been correlated with intercontinental travel and immigration. [1][2][3][4][5][6] According to the TN review only three cases were reported in Italy. Of these, two were considered imported.…”

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confidence: 99%

“…Of these, two were considered imported. [1][2][3][4] Confocal dermoscopy was performed in the third case, which resulted in two publications, but in both of them, the country of contagion was not mentioned. 3,4 This epidemiological data prompted us to contact the authors of the publications of the third case, 3,4 who informed us that the contagion most likely did not occur in Italy.…”

mentioning

confidence: 99%

“…[1][2][3][4] Confocal dermoscopy was performed in the third case, which resulted in two publications, but in both of them, the country of contagion was not mentioned. 3,4 This epidemiological data prompted us to contact the authors of the publications of the third case, 3,4 who informed us that the contagion most likely did not occur in Italy. In our patient, the infection is probably to be attributed to contact with sand in Sardinia, as H. werneckii has been isolated in…”

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confidence: 99%

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