Use of methotrexate in an exuberant case of confluent and reticulated papillomatosis of Gougerot and Carteaud in a teenager

Abstract

Confluent and reticulated papillomatosis of Gougerot and Carteaud is a rare dermatosis with onset during puberty, more prevalent in females than in males. The pathogenesis is unknown, but some theories suggest either a keratinization or endocrine disorder. The lesions are verrucous, brownish, hyperkeratotic papules or spots that coalesce in a confluent and/or reticulated pattern. This report presents a case with extensive cutaneous involvement associated with acanthosis nigricans and good response to treatment with methotrexate.

Resolution of confluent and reticulated papillomatosis after bariatric surgery

“…Other medications such as methotrexate 6 and topical tacrolimus 7 have been utilized with improvement of lesions; however further studies are needed to support their efficacy. The literature also supports weight loss as a factor in CARP resolution 2,8 ; however, there has not been a case report describing the effect of significant weight loss associated with bariatric surgery on this unusual dermatosis.…”