Nanoantimicrobials

Jampílek, Josef; Kráľová, Katarína

doi:10.1016/b978-0-323-46152-8.00002-0

Cited by 16 publications

(4 citation statements)

References 321 publications

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“…[9][10][11][12][13][14][15] The use of nanoparticles that encapsulate antibiotics shows great promise, potentially improving the efficacy of currently available compounds whilst reducing the risk of overuse leading to MDR bacteria. [16][17][18][19][20][21] The advantages of these nanoparticles include the fact that they may preferentially accumulate at infected sites due to poorly built neovasculature in diseased tissues which is commonly referred to as the enhanced permeability and retention (EPR) effect. 22,23 The EPR effect was rst observed in solid tumours where macromolecules and nanoparticles tend to accumulate in large quantities due to their increased vascular permeability and reduced lymphatic drainage.…”

Section: Introductionmentioning

confidence: 99%

Treatment of Staphylococcus aureus skin infection in vivo using rifampicin loaded lipid nanoparticles

Walduck

Sangwan

et al. 2020

RSC Adv.

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Section: Introductionmentioning

confidence: 99%

Treatment of Staphylococcus aureus skin infection in vivo using rifampicin loaded lipid nanoparticles

Walduck

Sangwan

et al. 2020

RSC Adv.

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“…On the one hand, a nanoparticle has specific properties such as its surface area, which can bind, absorb, and transport compounds. On the other hand, a nanosystem consist of two essential components: an active ingredient and a nanoparticle (nanocarrier) that stabilizes the active ingredient in the nanoform (Jampílek & Kráľová, 2017), which are collectively referred to as "nanopesticides" (Athanassiou et al, 2018;Benelli, Pavela, Maggi, Petrelli, & Nicoletti, 2017).…”

Section: Positive Effects Of Enp In Plantsmentioning

confidence: 99%

Effect of engineered nanoparticles on soil biota: Do they improve the soil quality and crop production or jeopardize them?

et al. 2020

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Nanoscience and nanotechnology have been shown to have the capacity to help study, manipulation,design, and synthesis of new nano-sized materials to manufacture new products with desirable features never seen before. The unique properties of materials at nanoscale opens an excellent possibility for nanotechnology to be used in soil environmental remediation, and water, and air decontamination. In crop management, nanomaterials are used to regulate the controlled release of nutrients, fertilizers, and pesticides. However, it is not only necessary to expose the positive effects by the application of the nanomaterials but also to demonstrate the impacts on soil and nontarget organisms (plants, mesofauna, macrofauna, and soil microbiota). In this context, pieces of evidence on the adverse effects of engineered nanoparticles (ENP) on the physicochemical and biological properties of soils are discussed in this paper. We have found a diversity of contradictory results. The summaries, findings, and conclusions of most of the investigations support the need to understand the biological or physicochemical transformation and transport of ENP in soil, and in the plant-organism relationship. Better understanding regarding the soil biota coupled with the ecological ENP behavior could ensure the safe use of ENP. Nanomaterials can change the physicochemical and biological properties of the soils; consequently, long-term in situ field trials are required, and meanwhile, land-application of nanomaterials should be limited to scientific experiments to fill knowledge gaps to not jeopardize the global food production or the environment and worldwide human health.

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“…NEs as stabilized heterogeneous systems of two immiscible liquids have a great potential in various biomedical applications; especially they are very attractive for drug delivery. Encapsulation in particular lipophilic drugs leads to the formation of therapeutic nanoformulations providing modification of bioavailability, alternative administration routes, release of drugs and, thus, a reduction of the required drug amount (e.g., Jampílek et al 2015b;Jampílek and Kráľová 2017b, 2019bPentak et al 2016;Patra et al 2018;Prasad et al 2017b;Prasad M et al 2018; Tayeb and Sainsbury 2018).…”

Section: Nanoemulsions Applicable In Medicinementioning

confidence: 99%

“…However, nanotechnology is increasingly being applied also in medicine, in theranostic and drug delivery (Prasad et al 2016;. By encapsulation into nanoformulations sustainable release of drugs as well as reduction of the required drug amount could be obtained and nanomaterials represent also an alternative approach to treating and mitigating infections caused by resistant bacteria (e.g., Jampílek et al 2015b;Jampílek and Kráľová 2017b, 2019bPentak et al 2016;Patra et al 2018;Prasad M et al 2018). In the food sector the nanotechnologies are used for food protection, including nanocomposites for protection of fruits, vegetables, cheese, dairy products, meat or fish, in smart active packaging, responsive packaging or edible coatings and like that significantly contribute to enhanced food quality.…”

Section: Introductionmentioning

confidence: 99%

Bio-Based Nanoemulsion Formulations Applicable in Agriculture, Medicine, and Food Industry

Jampílek

Kráľová

Campos

et al. 2019

Nanobiotechnology in Bioformulations

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Nanotechnology providing "a new dimension" accompanied with new properties conferred to many current materials is widely used for production of a new generation of agrochemicals, in medicine it enables improved drug bioavailability, reducing undesirable side effects, minimizing non-specific uptake and specific targeting to certain target cells, while in food industry it has great importance in food protection and biofortification of food with valuable ingredients. In biobased nanoemulsions belonging to lipid nanocarriers plant oils used for oil phase, emulsifiers, biosurfactants, cosurfactants, targeting ligands on the surface of nanoemulsion (e.g., folate) or encapsulated active ingredients are of natural origin. The biocomponents of such nanoemulsions show low toxicity to living organisms, could protect encapsulated compounds for degradation, ensure their sustainable release and reduce the amount of active ingredient necessary for required effect. This chapter presents a comprehensive current overview of recent findings in the field of nanoemulsions and their utilization in agriculture and food industry, with the main emphasis on formulations encapsulating essential oils or plant extracts suitable as effective pesticide preparations as well as medicinal applications of bio-based nanoemulsions, where attention is paid to transdermal nanoemulsion formulations, the use of nanoemulsions in cancer therapy and for pulmonary and ocular drug delivery. Nanoemulsions formulated with natural emulsifiers, biosurfactants and biopolymers are presented and bio-based nanoemulsions of essential oils and their constituents as well as nanoemulsions with encapsulated vitamins, fatty acids and some bioactive compounds are discussed. Applications of nanoemulsions in edible coatings are outlined as well.

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Nanoantimicrobials

Cited by 16 publications

References 321 publications

Treatment of Staphylococcus aureus skin infection in vivo using rifampicin loaded lipid nanoparticles

Treatment of Staphylococcus aureus skin infection in vivo using rifampicin loaded lipid nanoparticles

Effect of engineered nanoparticles on soil biota: Do they improve the soil quality and crop production or jeopardize them?

Bio-Based Nanoemulsion Formulations Applicable in Agriculture, Medicine, and Food Industry

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