A theoretical solution for the frictionless rolling contact of cylindrical biphasic articular cartilage layers

Ateshian, Gerard A.; Wang, Huiqun

doi:10.1016/0021-9290(95)00008-6

Cited by 174 publications

(141 citation statements)

References 31 publications

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“…The transport of interstitial fluid through cartilage has long been established from permeation experiments (Mansour and Mow 1976;Maroudas and Bullough 1968;Stockwell and Barnett 1964) or from measurements of the net loss of tissue weight under prolonged loading (Maroudas et al 1985). A more detailed examination of fluid flow patterns under various loading configurations has been estimated from theoretical and computational analyses which account for the porous-hydrated nature of cartilage (Ateshian et al 1994;Ateshian and Wang 1995;Hou et al 1992;Mow and Mansour 1977;Spilker et al 1992). Most of these models are concerned with the fluid flow profile within the ECM and do not explicitly incorporate chondrocytes.…”

Section: Introductionmentioning

confidence: 99%

A Theoretical Analysis of Water Transport Through Chondrocytes

Ateshian

Costa

Hung

2006

Biomech Model Mechanobiol

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Because of the avascular nature of adult cartilage nutrients and waste products are transported to and from the chondrocytes by diffusion and convection through the extracellular matrix. The convective interstitial fluid flow within and around chondrocytes is poorly understood. This theoretical study demonstrates that the incorporation of a semi-permeable membrane when modeling the chondrocyte leads to the following findings: Under mechanical loading of an isolated chondrocyte the intracellular fluid pressure is on the order of tens of Pascals and the transmembrane fluid outflow, on the order of picometers per second, takes several days to subside; consequently the chondrocyte behaves practically as an incompressible solid whenever the loading duration is on the order of minutes or hours. When embedded in its extracellular matrix, the chondrocyte response is substantially different. Mechanical loading of the tissue leads to a fluid pressure difference between intracellular and extracellular compartments on the order of tens of kilopascals and the transmembrane outflow, on the order of a nanometer per second, subsides in about one hour. The volume of the chondrocyte decreases concomitantly with that of the extracellular matrix. The interstitial fluid flow in the extracellular matrix is directed around the cell, with peak values on the order of tens of nanometers per second. The viscous fluid shear stress acting on the cell surface is orders of magnitude smaller than the solid matrix shear stresses resulting from the extracellular matrix deformation. These results provide new insight toward our understanding of water transport in chondrocytes.

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Section: Introductionmentioning

confidence: 99%

A Theoretical Analysis of Water Transport Through Chondrocytes

Ateshian

Costa

Hung

2006

Biomech Model Mechanobiol

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“…and Jin, 1986), boundary lubrication (Charnley, 1959;Radin et a/., 1970;Swann et a/., 1981), boosted lubrication (Walker et a/., 1968), weeping lubrication (McCutchen, 1959;McCutchen, 1962), biphasic self-generating lubrication (Mow and Lai, 1980), and biphasic boundary lubrication (Ateshian, 1997;Forster and Fisher, 1999;Ateshian et a/., 2003a;Graindorge et a/., 2004;Graindorge et a/., 2005). It is proposed that when mixed or boundary lubrication occurs (under high load and I or low sliding speed), the biphasic properties of cartilage play a significant role in reducing friction and enhancing lubrication (Ateshian and Wang, 1995;Forster and Fisher, 1999). …”

Section: Lubrication Mechanismsmentioning

confidence: 99%

“…Based on the biotribology of cartilage and diarthrodial jOints, it appears that a dominant mechanism for regulating the frictional response of articular layers is interstitial fluid pressurisation (Ateshian and Wang, 1995). There is strong support of this mode of lubrication in terms of experimental and theoretical evidence, which explain fundamental experimental findings, particularly the time dependence of the friction coefficient, and the ability to produce low friction at high loads and at any sliding velocity, including quasi-stationary loading.…”

Section: Biphasic I Triphasic Lubricationmentioning

confidence: 99%

“…This was due to the articular cartilage pin remaining loaded, therefore a large amount of load was carried by the fluid phase of the cartilage (Ateshian et a/., 1994). , 1994;Ateshian and Wang, 1995;Kelkar and Ateshian , 1999). When dynamic loading fluid movements were compared to the movements generated by constant loading in the hemiarthroplasty hip model , there was an additional influence due to the variation in the dynamic load cycle (Figure 5.34.a, green arrows).…”

Section: Friction and Frictional Shear Stressmentioning

confidence: 99%

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Tribology of Hemiarthroplasty

Lizhang¹

2013

Encyclopedia of Tribology

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“…Joints are composed of specialized connective tissues which, from a functional point of view, act synergistically, to effectively and efficiently deal with the mechanical loads, encountered over a lifetime [1,2]. One of the most important connective tissue, contributing to this normal articular function is articular cartilage.…”

mentioning

confidence: 99%

Effect of Age, Cartilage Health and Pain on the Isometric Strength of Knee Musculature: A Cross-Sectional Study

Singh¹,

Multani²,

Narula³

2017

IJPR

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Background of the Study: Knee muscle strength is a major contributor to the quality of life particularly in the elderly population. Various factors that can contribute to the strength needs to be examined, so that intervention can be taken at appropriate time to maintain the quality of life. Objectives of Study:The present study was conducted to investigate the relationship of age, pain and cartilage health on the isometric strength of knee flexors and extensors.Study Design: Cross-sectional study design Methodology: 320 subjects with age group 31-70 years were made part of study and were divided into 8 groups. Readings were noted down of age, VAS, height, weight, BMI, isometric strength of knee musculature and sonographic readings were noted down of cartilage clarity and interface of both knees. One time readings were taken.Results: Correlation analysis was performed to find association of cartilage clarity and interface, VAS and age with muscle strength. The r-value calculated came out to be significant for all the associations at P < 0.05. Conclusion:It can be concluded that the muscle strength is moderately associated with age and cartilage health and high association was noted with pain.

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A theoretical solution for the frictionless rolling contact of cylindrical biphasic articular cartilage layers

Cited by 174 publications

References 31 publications

A Theoretical Analysis of Water Transport Through Chondrocytes

A Theoretical Analysis of Water Transport Through Chondrocytes

Tribology of Hemiarthroplasty

Effect of Age, Cartilage Health and Pain on the Isometric Strength of Knee Musculature: A Cross-Sectional Study

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