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Aim of the study: To evaluate the anti-Inammatory activity of alcoholic extract of Cuscuta reexa stem on experimental animals Stems of Cuscuta reexa were collected, air dried and powdered.Materials and Methods: Methanolic extract was obtained by percolating the dried powder with 99.8% methanol. Alcoholic extracts of Cuscuta reexa stem (100mg/kg) was used as test drug. Anti-inammatory activity was on acute inammation was evaluated by carrageenan induced rat paw oedema method and chronic inammation was studied by Freund's complete adjuvant-induced arthritis method. For each of the studies albino rats of either sex weighing 100-200gms were divided into 3 groups with 5 animals in each group. Group A received normal saline 10 ml/kg. Test groups B, received alcoholic extracts of Cuscuta reexa stem (100mg/kg), Standard group C received Aspirin (100mg/kg). Acute oral toxicity test of the extract was performed as per OECD 425 (OECD Guidelines, 2001). The results were analysed by ANOVA followed by Dunnett'sResults: multiple comparison test. Alcoholic extracts of Cuscuta reexa stem (100mg/kg) showed signicant (p<0.01) anti-inammatory activity when compared to the control in carrageenan induced acute inammation. AECR was also effective in chronic arthritis model. TheConclusion: present study indicates that alcoholic extracts of Cuscuta reexa stem (100mg/kg) showed signicant (p<0.01) anti-inammatory activity against acute inammation as well as chronic inammation.
Aim of the study: To evaluate the anti-Inammatory activity of alcoholic extract of Cuscuta reexa stem on experimental animals Stems of Cuscuta reexa were collected, air dried and powdered.Materials and Methods: Methanolic extract was obtained by percolating the dried powder with 99.8% methanol. Alcoholic extracts of Cuscuta reexa stem (100mg/kg) was used as test drug. Anti-inammatory activity was on acute inammation was evaluated by carrageenan induced rat paw oedema method and chronic inammation was studied by Freund's complete adjuvant-induced arthritis method. For each of the studies albino rats of either sex weighing 100-200gms were divided into 3 groups with 5 animals in each group. Group A received normal saline 10 ml/kg. Test groups B, received alcoholic extracts of Cuscuta reexa stem (100mg/kg), Standard group C received Aspirin (100mg/kg). Acute oral toxicity test of the extract was performed as per OECD 425 (OECD Guidelines, 2001). The results were analysed by ANOVA followed by Dunnett'sResults: multiple comparison test. Alcoholic extracts of Cuscuta reexa stem (100mg/kg) showed signicant (p<0.01) anti-inammatory activity when compared to the control in carrageenan induced acute inammation. AECR was also effective in chronic arthritis model. TheConclusion: present study indicates that alcoholic extracts of Cuscuta reexa stem (100mg/kg) showed signicant (p<0.01) anti-inammatory activity against acute inammation as well as chronic inammation.
Herbal plants are those whose aromatic, medicinal, or nutritional qualities are highly valued. They have been utilized for innumerable years in conventional medicine and continue to be utilized as a natural alternative to conventional medicine. An extensive variety of herbal plants exist, each possessing distinct advantages. It is imperative to acknowledge that although herbal plants are generally regarded as secure, they may cause adverse effects or interactions with specific medications in some individuals. Be sure to seek the advice of a healthcare professional prior to utilizing herbal remedies. Abrus precatorious, possesses pharmacological properties that make it a promising candidate for the development of novel drugs, according to scientific research. Studies have shown, for instance, that extracts derived from the plant possess antibacterial, antitumor, and antidiabetic properties. A prevalent constituent of numerous tropical and subtropical ecosystems, especially in regions characterized by disturbed or degraded soils, is Abrus precatorius. It thrives in moist tropical forests and arid scrublands alike, and is renowned for its prolific development and ability to displace indigenous species. Abrus precatorius is therefore classified as an invasive species in numerous countries, such as Australia, Hawaii, and Florida. Nevertheless, due to its propensity for misuse, elevated toxicity, and invasive characteristics, this plant necessitates cautious handling and management. Pharmacological activities, chemical constituents, phytochemical analysis, and analytical techniques were the primary focuses of the present study.
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