10-year Incidence of Diabetes and Associated Risk Factors in Greece: the ATTICA study (2002-2012)

Koloverou, Efi; Panagiotakos, Demosthenes B.; Pitsavos, Christos; Chrysοhoou, Christina; Georgousopoulou, Ekavi; Pitaraki, Evangelia; Metaxa, V.; Stefanadis, Christodoulos

doi:10.1900/rds.2014.11.181

Cited by 34 publications

(41 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…During the 10-year follow-up period, 191 diabetes cases were documented (12.9%); 97 men and 94 women (13.4% vs. 12.4% respectively, p = 0.79 for gender difference) [11]. Additionally, 249 CVD cases were documented (13.8%); 153 men and 96 women (16.7% vs. 10.0% respectively, p < 0.001 for gender difference).…”

Section: -Year Diabetes and Cvd Incidence Among Participants With Pmentioning

confidence: 99%

See 1 more Smart Citation

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

et al. 2016

Self Cite

View full text Add to dashboard Cite

■ AbstractBACKGROUND: Prediabetes has been related to an increased risk of developing diabetes and cardiovascular disease (CVD). AIM: The aim of the present study was to examine the effect of the Mediterranean diet on diabetes and CVD risk in subjects with impaired fasting glucose (IFG, i.e. fasting plasma glucose 100-125 mg/dl). METHODS: During 2001-2002, 3042 men and women (>18y) were enrolled for the study. The participants showed no clinical evidence of CVD or any other chronic disease, and were living in the greater Athens (Greece) area. In 2011 and 2012, the 10-year follow-up examinations were performed, including a working sample of n = 1875 participants without diabetes at baseline. Adherence to the Mediterranean diet at baseline evaluation was assessed using the MedDietScore (range 0-55). RE-SULTS: The prediabetic subjects (n = 343) had a significantly higher incidence of diabetes (25% vs. 10%, p < 0.001) and CVD (17.8% vs. 12.3%, p = 0.007) compared with subjects with normal glucose values. A significant trend towards lower diabetes and CVD incidence was observed with medium and high adherence to the Mediterranean diet compared with low adherence (p < 0.001). High adherence to the Mediterranean diet (>35/55 score) was associated with lower 10-year incidence of diabetes and CVD. In multiple logistic regression models, participants with high levels of adherence to the Mediterranean diet were significantly less affected by diabetes and CVD than those with low adherence levels. CONCLUSION: High adherence to the Mediterranean diet is associated with a low risk of developing diabetes and CVD in prediabetic subjects.

show abstract

Section: -Year Diabetes and Cvd Incidence Among Participants With Pmentioning

confidence: 99%

“…Of these participants without diabetes at baseline, 279 (18.8%) had IFG and 1,206 (81.2%) were normoglycemic. Details of the aims, baseline procedures, and the 10-year follow-up examinations have been presented elsewhere [7,11].…”

Section: -Year Follow-up Evaluation (2011-2012)mentioning

confidence: 99%

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…In the Attica study [16], which continued until 2012, there was an increase in the incidence of DM. The 5-year incidence, from 5.5% in the period 2002-2007, amounted to 6.6% over the period 2007-2012.…”

Section: Incidence Type 2 Diabetes Mellitusmentioning

confidence: 99%

Trends in epidemiology of diabetes mellitus in Greece. Review of the major epidemiological studies

Loupa¹,

Kalantzi²,

Maris³

2017

Clin Case Rep Rev

View full text Add to dashboard Cite

Objective: A literature review of major publications was conducted to describe the epidemiology and trends over time of diabetes mellitus in Greece.Results: Although studies differ regarding methodology (self-reporting or data recording versus blood glucose measurements and OGTT), there is an increase in the prevalence of diabetes in the Greek population. In the Attica region, prevalence increased from 2,4% in 1974 to 9,5% (self-reporting studies) or 11,6% (blood glucose measurements and OGTT) in 2006. Regarding rural population, where prevalence was almost negligible (1,5%) during 1988-1993, there was a dramatic increase (approximately 11,7% during 2003-2005), to become equal to urban population. This change is similar to the trends worldwide. The cause of this increase is lifestyle change, with a consequent decrease in the physical activity, junk food, and obesity. Prevalence is higher in lower socioeconomic status. Intervention is important to decrease diabetes incidence by modifying modern lifestyle.

show abstract

“…he incidence of carbohydrate metabolism derangements and many cardiovascular and renal complications is increasing [1][2][3][4]. Various classes of drugs have proved useful in the management of patients with type 2 diabetes (T2D) and its complications [1,[5][6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Adverse Effects of GLP-1 Receptor Agonists

2014

View full text Add to dashboard Cite

■ AbstractGlucagon-like peptide-1 (GLP-1) receptor agonists are a class of injective anti-diabetic drugs that improve glycemic control and many other atherosclerosis-related parameters in patients with type 2 diabetes (T2D). However, the use of this relatively new class of drugs may be associated with certain adverse effects. Concerns have been expressed regarding the effects of these drugs on pancreatic and thyroid tissue, since animal studies and analyses of drug databases indicate an association of GLP-1 receptor agonists with pancreatitis, pancreatic cancer, and thyroid cancer. However, several meta-analyses failed to confirm a cause-effect relation between GLP-1 receptor agonists and the development of these adverse effects. One benefit of GLP-1 receptor agonists is that they do not cause hypoglycemia when combined with metformin or thiazolidinediones, but the dose of concomitant sulphonylurea or insulin may have to be decreased to reduce the risk of hypoglycemic episodes. On the other hand, several case reports have linked the use of these drugs, mainly exenatide, with the occurrence of acute kidney injury, primarily through hemodynamic derangement due to nausea, vomiting, and diarrhea. The most common symptoms associated with the use of GLP-1 receptor agonists are gastrointestinal symptoms, mainly nausea. Other common adverse effects include injection site reactions, headache, and nasopharyngitis, but these effects do not usually result in discontinuation of the drug. Current evidence shows that GLP-1 receptor agonists have no negative effects on the cardiovascular risk of patients with T2D. Thus, GLP-1 receptor agonists appear to have a favorable safety profile, but ongoing trials will further assess their cardiovascular effects. The aim of this review is to analyze critically the available data regarding adverse events of GLP-1 receptor agonists in different anatomic systems published in Pubmed and Scopus. Whenever possible, certain differences between GLP-1 receptor agonists are described. The review also provides the reader with structured data that compare the rates of the most common adverse effects for each of the various GLP-1 receptor agonists.

show abstract

10-year Incidence of Diabetes and Associated Risk Factors in Greece: the ATTICA study (2002-2012)

Cited by 34 publications

References 27 publications

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

Trends in epidemiology of diabetes mellitus in Greece. Review of the major epidemiological studies

Adverse Effects of GLP-1 Receptor Agonists

Contact Info

Product

Resources

About