10 / Comparison of Fresh Frozen Plasma (FFP) and Plasmalyte® for priming cardiopulmonary bypass in infants and children undergoing open-heart surgery: A double-blinded, randomised study.

Abstract

Background and goal of the studyFew studies in infants have investigated whether the addition of FFP to the cardiopulmonary bypass (CPB) priming shows advantages in terms of bleeding and transfusion. 1,2 We hypothesized that adding FFP to CPB priming is superior when compared with Plasmalyte ® . Material and methods Results and discussion Conclusions-The preliminary results of this first double-blinded study show that in small infants priming CPB with FFP does not show beneficial effects in terms of bleeding and transfusion requirements and can be avoided. -Our results need to be interpreted with caution as the baseline characteristics of the groups were not totally comparable.