1. Rat Bite Fever Causing Septic Arthritis and Osteomyelitis in a Young Man

Adizie, Tochi; Gayed, Mary; Ravindran, Jaya

doi:10.1093/rheumatology/keu096.001

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2021

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“…PubMed was searched for the following terms: Spirillum minus, Streptobacillus moniliformis, Haverhillia multiformis, rat bite fever, AND osteomyelitis, discitis. Our literature review uncovered associated with S. moniliformis, only 4 cases of osteomyelitis, 1 of possible osteomyelitis, and 4 of discitis, reported globally [6][7][8][9][10][11][12][13][14]. It is difficult to judge in our case whether the findings on MR imaging represent discitis or rather extension of infection from the L2-L3 endplate.…”

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confidence: 76%

Rat bite fever with osteomyelitis and discitis: case report and literature review

Adams

Mahapatra

2021

BMC Infect Dis

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Background Rat bite fever (RBF) is a rare systemic febrile illness transmitted by rats. Streptobacillus moniliformis is a pleomorphic Gram-negative bacillus which is the usual etiologic organism for rat bite fever in the United States. Case presentation Here we present a case of rat bite fever complicated by vertebral osteomyelitis and discitis. The patient revealed an exposure history of being bitten by pet rats. The patient’s symptoms dramatically improved with a six-week course of cephalexin therapy. Conclusions It is important to obtain a thorough zoonotic exposure history and maintain rat bite fever in the differential when considering potential causes of discitis and osteomyelitis.

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