1. Pathophysiology and Treatment for Autoimmune Thyroid Disease

Itoh, Mitsuyasu

doi:10.2169/naika.102.2355

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2017

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“…(1−2%) 13) , it is presumable not a few patients with chronic thyroiditis are latently positive for PR3-ANCA.…”

Section: Case Reportmentioning

confidence: 99%

A case of mixed connective tissue disease positive for proteinase 3 antineutrophil cytoplasmic antibody in a patient with slowly progressive type 1 diabetes mellitus and chronic thyroiditis

Michitsuji

Horai

Sako

et al. 2017

Jpn. J. Clin. Immunol.

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summaryA female in her sixties with slowly progressive type 1 diabetes mellitus (SPT1DM) and chronic thyroiditis was referred to our rheumatology department with swelling in her fingers. A prominent atherosclerotic lesion was revealed upon brain magnetic resonance imaging, and she was found to have mixed connective tissue disease (MCTD) positive for proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA). This rare case of MCTD accompanying SPT1DM and PR3-ANCA suggested that a synergy between MCTD and PR3-ANCA triggers atherosclerosis.

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“…(1−2%) 13) , it is presumable not a few patients with chronic thyroiditis are latently positive for PR3-ANCA.…”

Section: Case Reportmentioning

confidence: 99%