1-Methylimidazolium Trifluoroacetate Efficiently Catalyzed Three Component Synthesis of Diazaspiro[5.5]undecane-1,5,9-trione Derivatives under Solvent-Free Conditions

A convenient and efficient approach for the synthesis of 5-(1-phenyl-3-phenylprop-2-ynyl)-2,2-pentylidene-1,3dioxane-4,6-dione derivatives through a three-component reaction of aldehydes with 2,2-pentylidene-1,3-dioxane-4,6-dione and arylacetylene in the presence of Cu(OAc) 2 •H 2 O/Cu is described with 12 examples. The reaction tolerates a wide range of aldehydes furnishing the products with good to excellent isolated yields (65%～88%). Additionally, the synthetic protocol has the advantages of wild conditions, simple operation, and excessive copper reused.

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1-Methylimidazolium Trifluoroacetate Efficiently Catalyzed Three Component Synthesis of Diazaspiro[5.5]undecane-1,5,9-trione Derivatives under Solvent-Free Conditions

Abstract: by reaction of various aromatic aldehydes with urea and dioxanedione

Cited by 3 publications

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ChemInform Abstract: 1‐Methylimidazolium Trifluoroacetate Efficiently Catalyzed Three Component Synthesis of Diazaspiro[5.5]undecane‐1,5,9‐trione Derivatives under Solvent‐Free Conditions

ChemInform Abstract: 1‐Methylimidazolium Trifluoroacetate Efficiently Catalyzed Three Component Synthesis of Diazaspiro[5.5]undecane‐1,5,9‐trione Derivatives under Solvent‐Free Conditions

A One-Pot Four-Component Procedure for the Synthesis of Dispiro[tetrahydroquinoline-bis(2,2-dimethyl-1,3-dioxane-4,6-dione)] Derivatives

Efficent Synthesis of 5-(1-Phenyl-3-phenylprop-2-ynyl)-2,2-pentylidene-1,3-dioxane-4,6-dione Derivatives

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