1-Chloroacetyl-2,4-diphenyl-2,3-dihydro-1H-1,5-benzodiazepine

Abstract

Key indicatorsSingle-crystal X-ray study T = 120 K Mean '(C±C) = 0.007 A Ê Disorder in solvent or counterion R factor = 0.068 wR factor = 0.201 Data-to-parameter ratio = 15.2 For details of how these key indicators were automatically derived from the article, seeThe title compound, C 23 H 19 ClN 2 O, crystallizes as a racemic mixture having two molecules in the asymmetric unit. The structure is disordered.

2,4-Bis(4-chlorophenyl)-2-methyl-2,3-dihydro-1H-1,5-benzodiazepine

“…1). A similar boat structure is also observed in 1-Benzyl-4-(4-nitrophenyl)-2,3-dihydro-1H-1,5-benzodiazepine (Low et al, 2003) and 2,2,4-Trimethyl-2,3-dihydro-1H-1,5-benzodiazepine (Samanta et al, 1999). The atoms N1 and N2 are not coplanar with the adjacent aryl ring, as shown both by the N1-C1-C2-N2 torsion angle (4.1 (3) °), and by the deviations of the two N atoms (-0.015 (1) Å for N1 and -0.154 (2) Å for N2) from the plane of the aryl ring (C1/C2/C3/C4/C5/C6).…”

“…For related structures see: Braun et al (2000); Hormaza et al (2004); Cabral et al (1982); Braun & Muller (2004); Samanta et al (1999); Kaluski et al (1989). For related literature, see: Atwal et al (1987); Aversa et al (1986); Chimirri et al (1990); Di Braccio et al (2001); El-Sayed et al (1999); Kaluski et al (1989); Landquist (1984); Low et al (2003); Merluzzi et al (1990); Reddy et al (2000); Schutz (1982); Tranquillini et al (1997).…”