1-Benzylindoles as inhibitors of cytosolic phospholipase A<sub>2</sub>α: synthesis, biological activity, aqueous solubility, and cell permeability

Meyer zu Vilsendorf, Imke; Einerhand, Judith; Mulac, Dennis; Langer, Klaus; Lehr, Matthias

doi:10.1039/d3md00590a

RSC Med. Chem.

2024

DOI: 10.1039/d3md00590a

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1-Benzylindoles as inhibitors of cytosolic phospholipase A₂α: synthesis, biological activity, aqueous solubility, and cell permeability

Imke Meyer zu Vilsendorf,

Judith Einerhand,

Dennis Mulac

et al.

Abstract: Cytosolic phospholipase A2α (cPLA2α) is considered an interesting target for the development of new anti-inflammatory drugs, as it is significantly involved in the formation of pro-inflammatory lipid mediators. Recently, in...

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1-Benzylindoles as inhibitors of cytosolic phospholipase A₂α: synthesis, biological activity, aqueous solubility, and cell permeability

Abstract: Cytosolic phospholipase A2α (cPLA2α) is considered an interesting target for the development of new anti-inflammatory drugs, as it is significantly involved in the formation of pro-inflammatory lipid mediators. Recently, in...

Cited by 0 publications

References 28 publications

No citations

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1-Benzylindoles as inhibitors of cytosolic phospholipase A2α: synthesis, biological activity, aqueous solubility, and cell permeability

Abstract: Cytosolic phospholipase A2α (cPLA2α) is considered an interesting target for the development of new anti-inflammatory drugs, as it is significantly involved in the formation of pro-inflammatory lipid mediators. Recently, in...

Cited by 0 publications

References 28 publications

No citations

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Product

Resources

About

1-Benzylindoles as inhibitors of cytosolic phospholipase A₂α: synthesis, biological activity, aqueous solubility, and cell permeability