1‐Alkoxy‐2,5‐diphenylphospholane and ‐phospholanium Salts in Rhodium‐Catalyzed Asymmetric Hydrogenation

Abstract

A series of chiral enantiopure phosphinites was synthesized in four steps starting from phosphinic acid. New species were obtained as alkoxyphosphonium compounds. They can be used in the asymmetric hydrogenation of functionalized alkenes.

Coordination chemistry and catalysis with secondary phosphine oxides

“…Treatment of the phosphinous acid-borane with tetrafluoroboric acid 62,72 phospholane oxide-BF3 adduct reported by Toffano and co-workers. 73 Analysis of the crystal structure supports that the mechanism of deboronation 74 takes place by substitution of the hydrogen atoms of the borane group by fluorine, as suggested by…”

Regioselective Metal‐Catalyzed Hydrophosphinylation of Alkynes: Synthesis of Enantiopure α‐ or β‐Substituted Vinylphosphane Oxides

“…No other signals are detected. The presence of complex A is based on previous work 11b,11c,14. Furthermore, we observed no signal in the range from 0 to –30 ppm in the 1 H NMR spectrum, corresponding to the [Rh]–H bond 4a,7c,15.…”

Bis-(2,5-diphenylphospholanes) with sp2 Carbon Linkers: Synthesis and Application in Asymmetric Hydrogenation

“…It remained to activate the secondary phosphine oxide 12 to an electrophile suitable for reaction with 1,1‘-dilithioferrocene. This was accomplished by conversion of 12 to the 1-chlorophospholane 13 using phosphorus trichloride. This reactive intermediate was characterized by 1 H, 13 C{ 1 H}, and 31 P{ 1 H} NMR.…”