1-[4-(2,3,4,6-Tetra-O-acetyl-β-D-allopyranosyloxy)benzylidene]thiosemicarbazide

Abstract

Key indicators: single-crystal X-ray study; T = 292 K; mean (C-C) = 0.007 Å; R factor = 0.062; wR factor = 0.195; data-to-parameter ratio = 15.0.The title compound, C 22 H 27 N 3 O 10 S, was synthesized by reaction of an ethanol solution of helicid (systematic name: 4-formylphenl--d-allopyranoside), thiosemicarbazide and acetic acid. The molecule exhibits a trans conformation with respect to the C N double bond. The pyran ring adopts a chair conformation. In the crystal structure, the molecules are linked into chains parallel to the b axis by intermolecular N-HÁ Á ÁO hydrogen bonds. Related literature ExperimentalCrystal data

(E)-4-(β-D-Allopyranosyloxy)cinnamyl 4-bromophenyl ketone ethanol solvate

“…Some helicid derivatives have been reported to possess good biological activities (Sha & Mao, 1987). The synthesis and structure of some helicid derivatives heve been recently reported by our group (Fu et al 2009;Lv et al 2009;Yang et al 2009;Ye et al 2009). As a continuation of our studies in this area, we report herein the crystal structure of the title compound.…”