1,3-Dipolar Cycloaddition in a Series of 7-Oxoalkyl-1,3,7-Triazapyrenium salts

The aerobic oxidative annulation of chalcones, pyridines/isoquinoline and ethyl chloroacetate to indolizines was achieved by cascade reaction. Various functional groups on chalcones were tolerated. And different pyridines derivatives could also be suitable substrates. Ethyl chloroacetate is an essential component in participating of the oxidative annulation process. Overall, this protocol is very practical and efficient by using molecular oxygen as oxidant with high selectivity for the annulation product.

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Chloroacetate Promotes and Participates in the Oxidative Annulation of Pyridines/Isoquinoline by Using Oxygen as the Oxidant

Yue

Sun

Zhao

et al. 2016

Chemistry An Asian Journal

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ChemInform Abstract: 1,3‐Dipolar Cycloaddition in a Series of 7‐Oxoalkyl‐1,3,7‐triazapyrenium Salts.

et al. 2013

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Azapyrene-based fluorophores: synthesis and photophysical properties

et al. 2021

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1,3-Dipolar Cycloaddition in a Series of 7-Oxoalkyl-1,3,7-Triazapyrenium salts

Cited by 3 publications

References 6 publications

Chloroacetate Promotes and Participates in the Oxidative Annulation of Pyridines/Isoquinoline by Using Oxygen as the Oxidant

Chloroacetate Promotes and Participates in the Oxidative Annulation of Pyridines/Isoquinoline by Using Oxygen as the Oxidant

ChemInform Abstract: 1,3‐Dipolar Cycloaddition in a Series of 7‐Oxoalkyl‐1,3,7‐triazapyrenium Salts.

Azapyrene-based fluorophores: synthesis and photophysical properties

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