1,2,5-Thiadiazoles

3,6-Dibromopyridazine-4,5-diamine

“…The results are summarized in Table 1. The structure of diamine 2 was strictly confirmed by means of high resolution mass-spectrometry, 1 H, 13 C-NMR and IR spectroscopy, and mass-spectrometry.…”

“…Herein, we examined the reduction of this compound (Scheme 1). Sodium borohydride (NaBH4) or lithium aluminum hydride (LAH) were commonly used in the reductive cleavage of the 1,2,5-thiadiazole ring to ortho-diamine moiety [13]. We found that the treatment of pyridazine 1 with NaBH4 in EtOH in the presence of catalytic CoCl2•6H2O or with LAH in THF at reflux led to full decomposition of the starting material.…”

“…High-resolution MS spectrum was measured on a Bruker micrOTOF II instrument (Bruker Daltonik Gmbh, Bremen, Germany) using electrospray ionization (ESI). The measurement was performed in a positive ion mode (interface capillary voltage -4500 V) Sodium borohydride (NaBH 4 ) or lithium aluminum hydride (LAH) were commonly used in the reductive cleavage of the 1,2,5-thiadiazole ring to ortho-diamine moiety [13]. We found that the treatment of pyridazine 1 with NaBH 4 in EtOH in the presence of catalytic CoCl 2 •6H 2 O or with LAH in THF at reflux led to full decomposition of the starting material.…”

“…Supplementary Materials: The following are available online, 1 H, 13 C-NMR, IR and mass-spectra for the compound 2 are available online.…”

Direct Exchange of Oxygen and Selenium Atoms in the 1,2,5-Oxadiazoles and 1,2,5-Selenadiazoles by Action of Sulfur Monochloride

“…1,2,5-Thiadiazoles and particularly their benzo-fused derivatives have been known for many years, and their synthesis and applications in various branches of technology and medicine were extensively investigated and reviewed [1,2,3,4,5]. Recently, they were found to be an efficient electron acceptor and were used as the building blocks of many actual or potential molecule-based functional materials for organic electronics and spintronics [6,7,8,9,10,11,12].…”