1-(2,3,4-Trihydroxybenzylidene)thiosemicarbazide

Abstract

In the title mol­ecule, C8H9N3O3S, the thio­semicarbazide =N—NH—C(=S)—NH— fragment is twist a different degree of twist in the three independent mol­ecules [dihedral angles = 7.6 (1), 11.6 (1) and 20.7 (1)°]. Intra­molecular O—H⋯N and O—H⋯O hydrogen bonds occur. In the crystal, the hydr­oxy and amino groups are hydrogen-bond donors and the O—H⋯O, O—H⋯S and N—H⋯O hydrogen bonds generate a layer motif.

(E)-1-(4-Hydroxybenzylidene)-4-methylthiosemicarbazide

“…(Fang et al, 2007). The compounds 1-(2,3,4-trihydroxybenzylidene) thiosemicarbazide (Shawish et al, 2010a) and 1-(2,3,4-trihydroxybenzylidene)-4-ethylthiosemicarbazide (Shawish et al, 2010b) are analogous except for the presence of the ethyl group in the later compound. The present compound ( Fig.…”