051 Reducing particulate air pollution exposure in patients with coronary heart disease: improved cardiovascular health

Langrish, Jeremy P.; Li, X; Wang, S; Lee, Matthew M Y; Barnes, Gareth; Ge, Guangli; Miller, Mark R.; Cassee, Flemming R.; Boon, Nicholas A.; Donaldson, Kenneth; Li, J; Mills, Nicholas L.; Jiang, Lixin; Newby, David E.

doi:10.1136/hrt.2010.195958.25

Cited by 3 publications

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“…42 Indeed, it is encouraging that a number of studies have shown that reduction of personal exposure to urban PM through use of facemasks has been accompanied by improvements in cardiovascular parameters. 42,[56][57][58]242 Indoor air purifiers also appear to have beneficial effects in this regard, especially in cities with high levels of pollution. 42,243 The long-term consequences of these short-term benefits need to be established.…”

Section: Discussionmentioning

confidence: 99%

“…[51][52][53][54][55] Use of a facemask to lower exposure to particulate air pollution can attenuate these changes in HRV. [56][57][58] The findings from epidemiological studies, results from animal studies (see below), and preventative effects of beta-blocker therapy, 55,59 suggest that PM alters cardiac rhythm through imbalance of the autonomic nervous system to decrease the vagal tone and increased sympathetic tone. 60 PM exposure also exacerbates cardiac ischaemia, as demonstrated by ST segment depression.…”

Section: Particulate Matter and Cardiovascular Diseasementioning

confidence: 99%

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Air pollution and cardiovascular disease: car sick

Miller

Newby

2019

Cardiovascular Research

127

155

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The cardiovascular effects of inhaled particle matter (PM) are responsible for a substantial morbidity and mortality attributed to air pollution. Ultrafine particles, like those in diesel exhaust emissions, are a major source of nanoparticles in urban environments, and it is these particles that have the capacity to induce the most significant health effects. Research has shown that diesel exhaust exposure can have many detrimental effects on the cardiovascular system both acutely and chronically. This review provides an overview of the cardiovascular effects on PM in air pollution, with an emphasis on ultrafine particles in vehicle exhaust. We consider the biological mechanisms underlying these cardiovascular effects of PM and postulate that cardiovascular dysfunction may be implicated in the effects of PM in other organ systems. The employment of multiple strategies to tackle air pollution, and especially ultrafine particles from vehicles, is likely to be accompanied by improvements in cardiovascular health.

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Section: Discussionmentioning

confidence: 99%

Section: Particulate Matter and Cardiovascular Diseasementioning

confidence: 99%

Air pollution and cardiovascular disease: car sick

Miller

Newby

2019

Cardiovascular Research

127

155

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“…Additionally, while several medicines appear to have beneficial effects, the evidence is not strong enough for medicines to be viewed as being ‘protective’, especially against cardiovascular events. Interventions, such as facemasks, vehicle cabin filters or indoor air purifiers, may have a role here given emerging evidence suggesting that these can be effective at ameliorating the cardiovascular effects of air pollution to some degree ( Chen et al, 2015 ; Guan et al, 2018 ; Langrish et al, 2012 ; Langrish et al, 2009 ; Liu et al, 2018 ; Pettit et al, 2015 ; Yang et al, 2018 ), although further research is needed to establish the level of ‘protection’ they provide. This nuance of ‘protection’ versus ‘benefit’ requires careful messaging to prevent a false-sense-of-security that could lead to behavioural changes where an individual inadvertently places themselves at greater risk (e.g.…”

Section: Discussionmentioning

confidence: 99%

The cardiovascular effects of air pollution: Prevention and reversal by pharmacological agents

Miller

2022

Pharmacology & Therapeutics

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Source, Remediation and Health Effects of Nanoparticles in Urban Air

Uysal,

Ozunlu,

Kinayyigit

2023

Nanoparticles as Sustainable Environmental Remediation Agents

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Recent experimental results from various works proved that the emerging addition of nanosized fuel additives is an unsurpassed alternative to exhaust gas treatment devices for the reduction of toxic emissions. These nano-additives aid in the improvement of combustion characteristics along with an enhancement in the thermophysical properties, heat transfer rate, and stabilization of fuel mixtures. The first part of this chapter focuses on the comparison of efforts for emission reduction by using nanoparticle additives in various fuel derivatives. The nanoparticle additives mentioned herein are classified as metallic, non-metallic, oxygenated, carbonaceous, organic, and/or combined composition. The effects of nanoparticle shape, size, and dispersion as well as the optimum quantity of fuel additives on the emission characteristics are discussed. Furthermore, urban air studies are presented in the second part of this chapter with a special emphasis on traffic-based emissions. Finally, the toxic effects of airborne nano-pollutants on human health are discussed.

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051 Reducing particulate air pollution exposure in patients with coronary heart disease: improved cardiovascular health

Cited by 3 publications

References 0 publications

Air pollution and cardiovascular disease: car sick

Air pollution and cardiovascular disease: car sick

The cardiovascular effects of air pollution: Prevention and reversal by pharmacological agents

Source, Remediation and Health Effects of Nanoparticles in Urban Air

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