0029 The effects of preoperative 18F-FDG-PET/CT in breast cancer patients in comparison with conventional imaging study

18F-FDG PET/CT in breast cancer: Evidence-based recommendations in initial staging

“…Evidence level II, strong recommendation. [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] For more information, see Tables 3-5. 3a. 18F-FDG PET/CT should be used in high-risk patients, such as those with inflammatory BC.…”

Diagnostic Value of18F-FDG PET/CT in Comparison to Bone Scintigraphy, CT and18F-FDG PET for the Detection of Bone Metastasis

“…18 F-FDG PET should have better sensitivity and specificity than SPECT or BS because by imaging tumor metabolism directly with 18 F-FDG, detection may occur earlier than abnormal 99mTc-MDP accumulation, required for an identifiable bone reaction (Zaman et al, 2011;Lagaru et al, 2013). But some other reviewed that the sensitivity of PET was lower than BS (Choi et al, 2012;Montini et al, 2012). They regarded PET a possible tool to confirm positive results for conventional scans rather than a means of initial detection.…”

“…But there were conflicting evidences that 18 F-FDG PET was less sensitive than BS in breast and colon cancer. It seemed that the diagnosis value of PET was tumor specific (Shie et al, 2008;Choi et al, 2012;Montini et al, 2012). The morphological types of the metastasis lesions appeared to be relevant with FDG uptake, too.…”

Positron Emission Tomography/Magnetic Resonance Imaging for Local Tumor Staging in Patients With Primary Breast Cancer

“…9,10 Positron emission tomography/CT is primarily used for the detection of lymph node and distant metastases as well as for restaging of breast cancer patients, although promising results have been shown for response monitoring of neoadjuvant chemotherapy as well. [11][12][13] However, the value of integrated PET/CT for local breast cancer staging is limited due to low sensitivity in detecting small carcinomas and axillary lymph node metastases. 14,15 The recent introduction of integrated PET/MRI systems enables now a simultaneous high-quality assessment of the local tumor extent and metastatic spread, by combining the diagnostic advantages of MRI and PET.…”