“…In silico model of the dilutional effects of conventional component therapy versus whole blood in the management of massively bleeding adult trauma patients Jansen N. Seheult ,1,2 Michelle N. Stram, 1 Jason Sperry, 3,4 Philip C. Spinella, 5 Darrell J. Triulzi, 1,2 and Mark H. Yazer 1,2 BACKGROUND: There are multiple approaches to the blood product and fluid resuscitation of a bleeding trauma patient. An in silico model of different trauma resuscitation strategies was constructed to predict their effects on the volumes of the different body fluid compartments and on several important hemostatic factors.…”