The article presents review data of domestic and foreign scientific researchers on etiopathogenesis and clinical picture of chronic dermatosis - microbial eczema. Among chronic skin diseases, microbial eczema accounts for about 40%. According to the results of epidemiological studies, the incidence of microbial eczema among the inhabitants of the Russian Federation ranges from 6.0 to 15 cases per 1,000 people, which indicates a wide spread of this disease. The urgency of studying ME is conditioned by the persistent tendency to an earlier debut of the disease, weighting of the clinical picture, an increase in the number of relapses, and the spread of the pathological process on the skin. It should be noted that resistance to traditional methods of treatment used in microbial eczema is becoming more and more common. The above factors are the basis for further in-depth study of dermatosis and search for new effective treatment methods.
Eczema is a polyethyological disease that occurs as a result of the action of infectious and allergic, metabolic, neuroendocrine, vegetative and hereditary factors, clinically manifested by polymorphic rashes with a pronounced inflammatory reaction, accompanied by severe itching. Among all skin diseases of eczema takes the leading position, about 30-40 % of dermatological patients have this diagnosis. At the same time, every year there is a steady increase in the rate of eczema. Clinically effective is the use of complex treatment of eczema, which includes, in addition to standard pharmacological therapy, includes physiotherapeutic methods and spa factors, which together give a lasting positive therapeutic effect.
Quality of life indicators (QL) of patients are widely used in dermatological practice, but the influence of depressive and dissomnic symptoms on QL of patients with gender differences is not sufficiently studied.Objective: to identify depressive and dissominal symptoms in patients with psoriasis and evaluate its impact on the quality of life of these patients taking into account gender differences.Materials and methods: 34 patients with psoriasis were examined. Clinical examination included: analysis of complaints, medical history, assessment of dermatological status. Diagnosis of the presence and severity of depression was performed using a PHQ-9 patient health rating scale. Dissominal symptoms in patients with psoriasis were determined using the index of severity of insomnia ISI. To assess the quality of life, a dermatological index of quality of life (DLQI) was used.Results and discussion. Sleep disorders were detected in 15 patients (44.1%), depressive symptoms were determined in all patients, a negative effect of the disease on the quality of life of patients was found in 32 people (94.1%).Correlation analysis of data from the entire population of patients revealed statistically significant correlations of DLQI with the severity of depressive symptoms (r = 0.45, p = 0.008) and sleep disorders (r = 0.35, p = 0.04). In women, DLQI significantly correlates with the severity of depression (r = 0.48, p = 0.04) and tends to be associated with sleep disturbances (r = 0.43, p = 0.07). In men, the relationship between DLQI and indicators of depression and sleep disturbances is significantly weaker and is not statistically significant ((r = 0.34, p = 0.22) and (r = 0.17, p = 0.55), respectively).Conclusion.depressive symptoms and sleep disorders are interrelated with the quality of life of patients with psoriasis, and this relationship is more pronounced in women. Consequently, it is advisable to include effects aimed at normalizing mood and sleep in the program of complex therapy of psoriasis, taking into account gender differences.
The article outlines the questions of pathogenesis of acne as well as clinical trial data, which indicate that the skin of patients with acne needs comprehensive care with therapeutic cosmetics. Long term use of medical cosmetics has a positive effect on the course of acne disease. The basis of the study is the use of cosmetics line A “Skinormil” including the patented complex Citobiol lRIS, zinc sulfate and vitamin A. Seventy-four patients with acne of the first, second and third severity were monitored and it was recommended them a comprehensive skin care with medical cosmetics. According to the analysis of the clinical picture, it was concluded that on the background of proper care, there is a positive dynamics in the course of acne.
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