BackgroundAlthough the incidence of tuberculosis (TB) in most parts of China are well under control now, in less developed areas such as Qinghai, TB still remains a major public health problem. This study aims to reveal the spatio-temporal patterns of TB in the Qinghai province, which could be helpful in the planning and implementing key preventative measures.MethodsWe extracted data of reported TB cases in the Qinghai province from the China Information System for Disease Control and Prevention (CISDCP) during January 2009 to December 2016. The Kulldorff’s retrospective space-time scan statistics, calculated by using the discrete Poisson probability model, was used to identify the temporal, spatial, and spatio-temporal clusters of TB at the county level in Qinghai.ResultsA total of 48,274 TB cases were reported from 2009 to 2016 in Qinghai. Results of the Kulldorff’s scan revealed that the TB cases in Qinghai were significantly clustered in spatial, temporal, and spatio-temporal distribution. The most likely spatio-temporal cluster (LLR = 2547.64, RR = 4.21, P < 0.001) was mainly concentrated in the southwest of Qinghai, covering seven counties and clustered in the time frame from September 2014 to December 2016.ConclusionThis study identified eight significant space-time clusters of TB in Qinghai from 2009 to 2016, which could be helpful in prioritizing resource assignment in high-risk areas for TB control and elimination in the future.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-017-2643-y) contains supplementary material, which is available to authorized users.
Tourists’ perceptions of various risks at their travel destinations have crucial implications for destination management organizations and other tourism industry practitioners, which is growing into an unprecedented concern in the post-pandemic era. The Internet has boosted the global homestay industry. The perceived risk of homestay tourists requires further attention from researchers to promote the sustainable development of the homestay industry, especially in the post-pandemic era. To supplement and enrich the literature, this study aims to explore the relationships between tourists’ perceived risk, three dimensions of tourists’ emotional solidarity with hosts (feeling welcome, sympathetic understanding, and emotional closeness), and their customer loyalty towards the homestay industry in the post-pandemic era by taking the homestay industry of Guangzhou, China as the context, and employing SmartPLS for the empirical analysis. The results indicate that perceived risk has a significantly negative impact on emotional solidarity and customer loyalty, while emotional solidarity has a significantly positive impact on customer loyalty and plays a partial mediating role in the relationship between perceived risk and customer loyalty. The theoretical contributions of the article and the practical implications of the findings for the sustainable development of the homestay industry are discussed.
Two unusual flavonones coupled with styryl units, communins A (1) and B (2), and a new benzonaphthoxanthenone, ohioensin H (3), together with 11 known compounds, were isolated from the moss Polytrichum commune. The structures of 1-3 were assigned by spectroscopic data interpretation. The new compounds were evaluated for cytotoxicity against a small panel of cancer cell lines.
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