A [3+2] cascade cyclization reaction of pyridinium 1,4-zwitterionic thiolates and activated allenes was developed to access tetrasubstituted thiophenes.
Pyridinium 1,4-zwitterionic thiolates were applied to accessing indolizines via a sequence of annulation, oxidation and ring-contraction/desulfuration.
The synthesis of hydrobenzoimidazoles from para‐quinamines and 1,3,5‐triazinanes was achieved via a formal [3+2] annulation reaction in the presence of In(OTf)3 as the catalyst. Further studies demonstrated that the synthesis of hydrobenzooxazoles could also be accomplished via the same strategy from para‐quinols and 1,3,5‐triazinanes.
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