Ðåôåðàò Ìåòà. Âèâ÷èòè îñîáëèâîñò³ õàðàêòåðèñòèêè êë³í³÷íî-ôóíêö³îíàëüíîãî ñòàíó íîâîíàðîäaeåíèõ ä³òåé ç âðîäaeåíèìè âàäàìè ñåðöÿ. Ìàòåð³àë ³ ìåòîäè. Ïðîâåäåíî ðåòðîñïåêòèâíèé àíà-ë³ç ìåäè÷íî¿ äîêóìåíòàö³¿ ç àíàë³çîì ñòàíó äèòèíè ïðè íàðîäaeåí³, ïåðåá³ãó ðàííüîãî íåîíàòàëüíîãî ïå-ð³îäó, îö³íêîþ àíòðîïîìåòðè÷íèõ ïîêàçíèê³â íîâîíàðîäaeåíèõ ä³òåé ç âðîäaeåíèìè âàäàìè ñåðöÿ çà ïå-ð³îä 2011-2015 ðîêè òà ïîð³âíÿíî ö³ ïîêàçíèêè ç àíà-ëî´³÷íèìè ó êîíòðîëüí³é ãðóï³ çäîðîâèõ íîâîíàðîäaeåíèõ ä³òåé. Äîñë³äaeåííÿ ´ðóíòóâàëîñÿ íà äàíèõ ïîëîãîâîãî â³ää³ëåííÿ Ëüâ³âñüêî¿ îáëàñíî¿ êë³í³÷íî¿ ë³êàðí³, äå êîíöåíòðóþòüñÿ ae³íêè ç âðîäaeåíîþ ïàòîëî´³þ ïëîäó òà âàã³òí³ ç åêñòðà´åí³òàëüíîþ ïàòîëî´³ºþ Ëüâ³âñüêî¿ îáëàñò³. Ðåçóëüòàòè é îáãîâîðåííÿ. Ó ïîëîãîâîìó â³ää³ëåíí³ çà 5 ðîê³â íàðîäèëîñü 172 ä³òåé ç âðîäaeåíèìè âàäàìè ñåðöÿ ñåðåä 15429 ä³òåé, ÿê³ íàðîäèëèñÿ aeèâèìè. ×àñòîòà ïàòîëî´³¿ ñêëàäàëà 1,1. Ñåðåä íîâîíàðîäaeåíèõ ä³òåé îáîõ ãðóï íå áóëî ñóòòºâî¿ ð³çíèö³ â ê³ëüêîñò³ ä³òåé ÷îëîâ³÷î¿ òà ae³íî÷î¿ ñòàò³.  êîíòðîëüí³é ãðó-ï³ óñ³ ä³òè áóëè äîíîøåíèìè, â òîé ÷àñ ó îñíîâí³é ãðóï³ 16,7% ä³òåé áóëè íåäîíîøåíèìè (p<0,05). Ó ãðó-ï³ ä³òåé ç âðîäaeåíèìè âàäàìè ñåðöÿ ñïîñòåð³ãàëàñÿ òåíäåíö³ÿ äî íàðîäaeåííÿ ä³òåé ç ìàëîþ ìàñîþ äëÿ ïåâíîãî ãåñòàöiéíîãî â³êó, à òàêîae áóëî ñóòòºâî á³ëüøå ä³òåé çðîñòîì 40-44 ñì ó ïîð³âíÿíí³ ç çäîðîâèìè ä³òüìè (p<0,05).
The research aim is to study factors of perinatal complications among women with diseases of the urinary system on the basis of retrospective analysis of their newborns' condition. Materials and Methods. A total of 160 women with urinary diseases were selected for the study in Lviv Regional Clinical Hospital from 2014 to 2017. We studied the development of infants born to women with a clinical diagnosis of "Diseases of the urinary system". The newborns' gestational age at birth, anthropometric indicators, and condition assessment on the Apgar scale were analyzed. The obtained indicators were compared with similar parameters in the control group of healthy women that had given birth to live children in the same maternity department during the same period of time. Results and Discussion. We analyzed the condition of infants born to 130 women with urinary diseases. 68 of them were hospitalized with pyelonephritis, and 62 - with chronic pyelonephritis. The control group included 30 healthy female patients. The gestation age analysis showed that the number of preterm babies was higher in the group of infants born to mothers with acute pyelonephritis - 13 cases (10.0%) and even much higher in the group of mothers with chronic pyelonephritis - 25 cases (19.2%). These results were compared with the data obtained from the control group in which 30 full-term babies (100.0%) were born, (p <0.05). In the group of women with acute pyelonephritis, the majority of infants were born with the body weight more than 2500.0 g - 55 cases (42.3%), and 13 (10.0%) infants with the birth weight less than 2500.0 g. The mothers with chronic pyelonephritis gave birth to infants with the body weight less than 2500.0 g in 37 cases studied (28.5%). There was also a significant number of low birth weight newborns in this group - 25 cases (19.2%). In the control group, all 30 babies (100.0%) were born healthy weighing over 2500.0 g. Infants receiving less than 7 points on the Apgar scale were born to women with acute pyelonephritis in 15 cases (11.5%) and to mothers with chronic pyelonephritis in 25 cases (19.2%). In the group of healthy women, all newborns' condition was satisfactory. Conclusions. Women with urinary pathology are confirmed to be at risk of perinatal complications. The research has revealed the significant differences in gestational age, birth weight, and the Apgar score among infants born to women in the main and control groups (p<0.05). The infants whose mothers suffered from urinary pathology were often born prematurely: 13 (10.0%) - to mothers with acute pyelonephritis and 25 (19.2%) - to mothers with chronic pyelonephritis. At the same time the infants in the control group were born healthy (100.0%). Therefore, women with urinary pathology are recommended to be included in the "risk group" for perinatal complications.
The aim of the study was to determine the maternal factors of perinatal complications in women with diseases of the urinary system. A group of women with pathology of the urinary system were studied during the course and completion of pregnancy. The complications in childbirth condition of newborns in comparison with similar indicators in healthy women were also assessed. It was found that most women with urinary tract pathology that were pregnant again, had complications of somatic (most often a combination of urinary tract pathology and chronic infectious diseases) and reproductive history (most often – miscarriages). Women with complications during pregnancy, pyelonephritis, anemia, and the threat of abortion were significantly more often registered in the main group (p<0.05). Women in the main group were significantly more likely to have premature births: 15.4% of women with acute pyelonephritis and 46.2% of women with chronic pyelonephritis, while all women in the control group gave birth on time (P<0.05). Significantly more women in the main group had complications in childbirth: most often – weakness of labor – I group 8 (6.2%), II – 9 (6.9%). Termination of pregnancy in the vast majority of women in the main group was physiological, cesarean delivery was completed in 3 (2.3%) women in group I and 10 (7.7%) women in group II. All women in the control group had timely, physiological births. The condition of newborns of mothers with pathology of the urinary system was often disturbed. A significant proportion of children from the main group (I – 5.4%, II – 10.0%) required immediate resuscitation measures at birth and their transfer to specialized departments for further treatment.
Aim. The purpose of this paper is to study reproductive function in women with menstrual disorders. Material and Methods. We analyzed the data and results of medical and genetic counseling of 107 women with menstrual dysfunction who applied to the medical and genetic center of the State Institution "The Institute of Hereditary Pathology of the National Academy of Medical Sciences of Ukraine". When analyzing the obtained indicators, we compared them with similar parameters in the comparison group which consisted of 100 healthy women applying for family planning. In the course of the work the data of somatic, gynecological and reproductive anamnesis were studied. Statistical processing of the obtained results was performed using the application package "Statistica 7.0" and the standard package of Excel 2013 statistical analysis. Significance between different groups was investigated by Pearson's test c2. Differences were considered significant at a significance level of p <0.05. Results and Discussion. Data and results of the medical and genetic counseling of 107 women with menstrual dysfunction (the main group) and 100 women without menstrual dysfunction (the control group) were analyzed. Data of somatic, gynecological and reproductive anamnesis were studied. Significant differences were found in the social status of women of two groups (р<0,05): in the main group, there were 60 working women (56.1%) and 44 (41.1%) housewives. In the control group, there were 32 working women (32.0%) and 68 (68.0%) housewives respectively. The study of the features of menstrual function showed significant differences in the formation and duration of the menstrual cycle in women of both groups (p<0.05). In women with menstrual dysfunction, there were disorders of reproductive history, most often due to miscarriages and stillbirths - 59 (55.1%) and infertility - 19 (17.7%). It was found that most patients in the main group had somatic diseases: 66 (61.7%) in the main group and 46 (46.0%) in the control group (р<0.05). Complications of gynecological anamnesis were significantly more often observed in women of the main group - 85 (79.4%) than in women of the control group - 41 (41.0%) (р<0.05). Conclusions. Analysis of the social status of women in both groups showed that the vast majority of women in the main group were employees compared to women in the control group: 60 (56.1%) and 44 (32.0%) against 32 (32%) and 44 (44, 0%) respectively (p <0,05). Significant differences in menstrual function data in women of both groups were found. A considerable proportion of women in the main group - 52 (48.0%) noted the onset of menarche at the age of 15 years, and in most women of the control group - 91 (91.0%) it was observed at the age of 12-14 years, and only in 9 (9.0%) cases - at the age of 15 years (p <0.05). There were significant differences in the duration of the menstrual cycle on all indicators in women of both groups. In 48 (44.9%) women of the main group, the duration of the menstrual cycle was 35-45 days, and in 12 (11.2%) - 45-90 days. In all women of the control group, this figure was 28-35 days (p <0.05). Only in 66 (61.7%) patients of the main group, the cycle was established immediately, compared with 81 (81.0%) women in the control group (p <0.05). Women in the main group were significantly more likely to have complications of reproductive history - 63 (58.9%): most often miscarriages and stillbirths - 59 (55.1%) and infertility - 19 (17.7%) (p <0.05). 85 (79.4%) women of the main risk group had difficult gynecological history, compared to 41 (41.0%) in the control group and they were significantly more likely to suffer from infertility -19 (17.7%), p <0.05).
Мета роботи-вивчити частоту уродженої патології системи кровообігу в новонароджених дітей за 2011-2015 рр. у пологовому відділенні Львівської обласної клінічної лікарні. Матеріал і методи. Проведений аналіз 342 історій пологів жінок, що народили дітей із уродженими вадами серця та карт новонароджених дітей за 5 років. Результати. Частота народження дітей із уродженими вадами серця за період з 2011 до 2015 років становила 1,0-1,3%. Встановлено, що достовірно частіше дана патологія спостерігалась у жінок віком старше 35 років та траплялась майже з однаковою частотою у хлопчиків та дівчаток. Діти з уродженими вадами розвитку серця достовірно частіше народжувались недоношеними. Висновки. Перинатальна патологія за рахунок уроджених вад розвитку серцево-судинної системи становила 1,0%-1,3% серед загальної кількості новонароджених дітей. Відсутня позитивна тенденція до зниження уродженої патології населення за рахунок питомої ваги уроджених хвороб системи кровообігу.
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