Recent results of the searches for Supersymmetry in final states with one or two leptons at CMS are presented. Many Supersymmetry scenarios, including the Constrained Minimal Supersymmetric extension of the Standard Model (CMSSM), predict a substantial amount of events containing leptons, while the largest fraction of Standard Model background events -which are QCD interactions -gets strongly reduced by requiring isolated leptons. The analyzed data was taken in 2011 and corresponds to an integrated luminosity of approximately L = 1 fb −1 . The center-of-mass energy of the pp collisions was √ s = 7 TeV.
DELPHI (DEtector with Lepton, Photon and Hadron Identication) is a detector for e + e physics, designed to provide high granularity o v er a 4 solid angle, allowing an eective particle identication. It has been operating at the LEP (Large Electron-Positron) collider at CERN since 1989. This article reviews its performance.(To be submitted to Nucl. Inst. and Meth.) ii
We have measured the production cross-section times branching ratio for J/ψ→μ+μ- in pp̄ interactions at √s=630 GeV in the kinematic range |y| <2.0 and pT> 5 GeV/c, BR(J/ψ→μ+μ -)σ(pp̄→J/ψ)=6.18±0.24±0.81 nb. The data sample collected in 1988 and 1989 for an integrated luminosity of 4.7 pb-1 represents a fivefold improvement over the statistics in our earlier study of the J/ψ production process, and the pT distribution which is measured extends to 28 GeV/c. Using event topology we show that the rate for the direct production of J/ψ, via radiative decays of χ states, is larger than that for production via B-hadrons. Production of ψ′ is also studied using the decay modes ψ′→μ+μ- and ψ′→J/ψπ+π-
Purpose: Prostate cancer is as far the most prevalent male cancer. Rutin (a glycoside from quercetin flavonoid) displays antioxidant activity leading to cell apoptosis. Combined effects of rutin with the widely used anti-cancer drug, 5-fluorouracil (5-FU), on prostate cancer cell line (PC3) was investigated herein. Methods: Different concentrations of combined 5-FU and rutin were applied to PC3 cells compared to separate treatment for 48 hours. Cell viability, as well p53 gene expression respectively were assessed by MTT assay and real-time quantitative polymerase chain reaction (qPCR). Changes of Bcl-2 signal protein and apoptosis were determined using western blot and flow cytometry procedures, respectively. Clonogenic assay was used to colony counts assessment. Results: 50% inhibitory concentration (IC50) of separate cell treatment with either rutin and 5-FU respectively were 900 μM and 3Mm, while combination index (CI) of combined 5-FU /rutin application reached a level of synergistic effects (0.33). Combination of 5-FU/rutin enhanced apoptosis and p53 gene expression in PC3 cells. PC3 cell colony counts and Bcl-2 signaling protein were decreased by 5-FU/rutin combination. Conclusion: Synergistic effects of 5-FU/rutin combination on PC3 cells line enhanced apoptosis, p53 gene expression, and down-regulation of Bcl-2 protein, compared to control separate application. 5-FU/rutin combination does seem an interesting therapeutic pathway to be further investigated.
We report measurements of b-quark and B-hadron production in pp collisions at √s=630 GeV. We use muon data samples to extract beauty production cross-sections over a wide range of transverse momentum in the central rapidity range y < 1.5. We compare our results to an O(αs 3) QCD prediction and find good agreement over the measured b-quark transverse momentum range 6 GeV/c to 54 GeV/c. Using the shape of the pT and y distributions predicted by QCD to extrapolate our data, we infer a total cross-section for b-quark production at √s=630 GeV of σ(pp̄→bb̄+X)=19.3±7(exp.)±9(th.)μb
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