No abstract

A high incidence of arrhythmic events was observed at 1-year follow-up in close to one-half of the patients with LBBB post-TAVR. Significant bradyarrhythmias occurred in one-fifth of the patients, and PPM was required in nearly one-half of them. These data support the use of a cardiac monitoring device for close follow-up and expediting the initiation of treatment in this challenging group of patients. (Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation [MARE study]: NCT02153307).

Introduction The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a severe respiratory disease with a 3% global mortality. In the absence of effective treatment, controlling of risk factors that predispose to severe disease is essential to reduce coronavirus disease 2019 (COVID-19) mortality. Large observational studies suggest that exercise can reduce the risk of all-cause and disease-specific mortality. The aim of this study was to analyze the influence of the baseline physical activity level on COVID-19 mortality Methods This is a retrospective cohort study that included patients between 18 and 70 years old, diagnosed with COVID-19 and hospitalized in our center between February 15 and April 15, 2020. After discharge all the patients included in the study were contacted by telephone. Baseline physical activity level was estimated using the Rapid Assessment of Physical Activity Scale questionnaire and patients were divided into two groups for comparison: sedentary patients (group 1) and active patients (group 2). Results During the study period 552 patients were admitted to our hospital and met the inclusion criteria. Global mortality in group 1 was significantly higher than in group 2 (13.8% vs 1.8%; p < 0.001). Patients with a sedentary lifestyle had increased COVID-19 mortality independently of other risk factors previously described (hazard ratio 5.91 (1.80–19.41); p = 0.003). Conclusion A baseline sedentary lifestyle increases the mortality of hospitalized patients with COVID-19. This finding may be of great utility in the prevention of severe COVID-19 disease.

Questo protocollo ha l'obiettivo di fornire una guida per la gestione delle sale di Emodinamica e del personale ad esse afferente, che consenta di garantire idonei livelli di trattamento ed al contempo l'applicazione di tutte le misure di prevenzione e controllo delle infezioni durante la gestione dei casi SOSPETTI, PROBABILI o CONFERMATI di infezione da virus 2019-nCoV NON DIFFERIBILI (per i quali il trattamento interventistico non può attendere il risultato del tampone che dovrà comunque essere processato con priorità). Si intende per caso SOSPETTO il paziente che: A) Presenta uno o più dei seguenti sintomi: febbre o tosse o difficoltà respiratoria Associato a B) Contatto stretto* di un caso confermato di COVID-19 oppure essere stato in zone con presunta trasmissione comunitaria diffusa o locale. Si intende per caso PROBABILE il paziente che: presenti caratteristiche di SOSPETTO + risultato test dubbio o inconcludente.Per caso CONFERMATO si intende paziente con conferma di laboratorio indipendentemente dalla presenza di segni e sintomi clinici.*Definizione di contatto stretto (il collegamento epidemiologico può essere avvenuto entro un periodo di 14 giorni prima dell'insorgenza della malattia):