The concept of mesenchymal stem cells (MSCs) is becoming increasingly obscure due to the recent findings of heterogeneous populations with different levels of stemness within MSCs isolated by traditional plastic adherence. MSCs were originally identified in bone marrow and later detected in many other tissues. Currently, no cloning based on single surface marker is capable of isolating cells that satisfy the minimal criteria of MSCs from various tissue environments. Markers that associate with the stemness of MSCs await to be elucidated. A number of candidate MSC surface markers or markers possibly related to their stemness have been brought forward so far, including Stro-1, SSEA-4, CD271, and CD146, yet there is a large difference in their expression in various sources of MSCs. The exact identity of MSCs in vivo is not yet clear, although reports have suggested they may have a fibroblastic or pericytic origin. In this review, we revisit the reported expression of surface molecules in MSCs from various sources, aiming to assess their potential as MSC markers and define the critical panel for future investigation. We also discuss the relationship of MSCs to fibroblasts and pericytes in an attempt to shed light on their identity in vivo.

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The fifth-generation (5G) networks are expected to be able to satisfy users' different quality-ofservice (QoS) requirements. Network slicing is a promising technology for 5G networks to provide services tailored for users' specific QoS demands. Driven by the increased massive wireless data traffic from different application scenarios, efficient resource allocation schemes should be exploited to improve the flexibility of network resource allocation and capacity of 5G networks based on network slicing. Due to the diversity of 5G application scenarios, new mobility management schemes are greatly needed to guarantee seamless handover in network slicing based 5G systems. In this article, we introduce a logical architecture for network slicing based 5G systems, and present a scheme for managing mobility between different access networks, as well as a joint power and subchannel allocation scheme in spectrum-sharing two-tier systems based on network slicing, where both the co-tier interference and cross-tier interference are taken into account. Simulation results demonstrate that the proposed resource allocation scheme can