Background: The present study was undertaken to investigate whether the transcutaneous electrical stimulation of the P6 acupoint prevents postoperative nausea and vomiting (PONV) after minor breast surgery.Methods: In this prospective, randomized, double-blind and placebo-controlled study, we investigated ASA I or II female patients who underwent minor breast surgery under general anesthesia using sevoflurane. We used a ReliefBand Ⓡ device (NSTTM 600, Woodside Biomedical Inc, USA) for the transcutaneous electrical stimulation of the P6 acupoint. The patients were randomly divided into two groups; in the P6 group (n = 33) the activated ReliefBand Ⓡ was placed at the P6 acupoint; in the placebo group (n = 33) the inactivated ReliefBand Ⓡ was placed at the P6 acupoint. The ReliefBand Ⓡ was applied 10 min before the end of surgery and it remained in place for 24 h. We evaluated the incidence and severity of PONV, and the need for palliative antiemetics during the first 6 h and 24 h after surgery.Results: The incidence of nausea was significantly lower in the P6 group (33%) than in the placebo group (67%) during the first 24 h after surgery. The severity of nausea was also significantly lower in the P6 group than in the placebo group. However, the incidence of vomiting and the need for palliative antiemetics was not different between the two groups.Conclusions: Transcutaneous electrical stimulation of the P6 acupoint significantly reduced the incidence and severity of nausea, but not the incidence and severity of vomiting, for female patients undergoing minor breast surgery during the first 24 h after surgery.
Background:The aim of the present study was to investigate the effect of preemptive gabapentin on postoperative pain and opioid consumption in patients undergoing mastectomy.Methods: In a randomized, double-blind study, 41 patients received a single dose of oral gabapentin 900 mg with routine premedicantion (GABA group, n = 21) or only routine premedication without gabapentin (control group, n = 20) 1 h before surgery. Patients received intravenous patient-controlled analgesia using fentanyl for postoperative analgesia. VAS scores for pain at rest and during movement, sedation scores, side effects, and fentanyl consumptions were assessed at 6 and 24 h after surgery.Results: No significant differences were found between the two groups in terms of pain scores, side effects, or fentanyl consumptions for 24 h postoperatively. However, patients in the GABA group were more sedated at 6 h postoperatively than patients in the control group (P < 0.05).Conclusions: The preemptive administration of oral gabapentin at 900 mg did not reduce postoperative pain or fentanyl consumption after mastectomy during the 24 h period following surgery.
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