Acylation of the amine (I) gives the cephalosporanates (III), whose methylthio group is replaced by formamido in a two‐step process to give the formamides (V), which are converted to their sodium salts (VIa).
Additionsreaktion des Mischanhydrids (IV) mit der aus den Komponenten (I) und (II) erhältlichen Schiffbase (III) gibt die isomeren Lactame (Va) (3 z2‐Isomerengemisch) und (Vb) + (Vc); (Vb) wird dann wie angegeben in die Titelverbindung (IXa) übergeführt.
scite is a Brooklyn-based startup that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.