Colistin administration appears to be efficacious in VLBW infants; however, renal function tests and serum electrolytes should be monitored more closely in these infants during treatment.
ÖZETBu ça lış ma da, S.B. İz mir Te pe cik Eği tim ve Araş tır ma Has ta ne si Ço cuk Acil Ser vi si'nin bir yıl lık ça lış ma sı nın de ğer len diril me si amaç lan mış tır. 01.01.2011 -31.12.2011 ta rih le ri ara sın da ço cuk acil ser vi si ne baş vu ran ol gu la rın de mog ra k ve tıb bi bil gi le ri has ta ne oto mas yon sis te min den ge ri ye dö nük ola rak el de edil miş tir. Ta nı lar da ICD-10 ta nı ko du sis te mi kul la nıl mış tır. Top lam 179002 has ta (%55,8'i er kek) acil ser vi se baş vur du. Has ta lar yaş grup la rı na gö re de ğer len di ril di ğin de, %68,1'ini 1 ay -5 yaş gru bu ço cuk la rın oluş tur du ğu sap tan dı. Ol gu la rın %51'inin 16.00-24.00 sa at le ri ara sın da ço cuk acil ser vi sine baş vur du ğu gö rül dü. En çok baş vu ru nun Ara lık (22 129 ol gu), en az baş vu ru nun ise Ağus tos (12588 ol gu) ay la rın da ya pıl dı ğı sap tan dı. Top lam 22 585 ol gu nun (%12,6) trav ma ne de niy le baş vur du. 375 ol gu (%0,2) ze hir len me ta nı sı nı aldı. Baş vu ran ol gu la rın %10'u göz lem bi rim de iz len di. Top lam 23 559 adet kon sül tas yon is te mi ya pıl dı. En sık kon sül tasyon is te nen bi rim or to pe di ve trav ma to lo ji kli ni ğiy di (9020 ol gu, %38,2). Ol gu la rın %3,5'i has ta ne ye ya tı rıl dı. Ço cuk acil ser vi si ne en sık baş vu ru se bep le ri nin akut fa ren jit (%16,3), so ğuk al gın lı ğı (%15) ve trav ma (%12,6) ol du ğu gö rül dü. Toplam 20 ol gu ya ile ri ya şam des te ği ya pıl dı ve 5 ol gu acil ser vis te öl dü. Has ta ne miz ço cuk acil ser vi sin den el de edi len bil gi ler, acil de ça lı şan dok tor ve hem şi re le rin bü yük bir iş yü kü ile kar şı kar şı ya kal dık la rı nı gös ter mek te dir. Bu prob le min çö zü mü ül ke ge ne lin de ve has ta ne için de ye ni dü zen le me le rin ya pıl -ma sıy la müm kün ola cak tır CAYD 2014;1(2):65-71. Anah tar Ke li me ler: Acil ser vis, kalabalık acil, ço cuk SUM MARYThe ob jec ti ve of the study was to analy ze the one-ye ar ac ti vity of the Pe di at ric Emer gency De part ment of the Mi nistry of He alth Iz mir Te pe cik Te ac hing and Re se arch Hos pi tal. De mog rap hic and me di cal in for ma ti on of the chil dren ad mit ted to Pe di at ric Emer gency De part ment of the Te pe cik Training and Re se arch Hos pi tal bet we en 01.01.2011-31.12.2011 was ob tai ned thro ugh hos pi tal au to ma ti on system, retros pec ti vely. ICD-10 co ding system is used for di ag no sis. A to tal of 179 002 (55.8% ma le) pa ti ents we re ad mit ted to the pe di at ric emer gency de part ment. When pa ti ents were eva lua ted ac cor ding to age gro up, 68.1% of the pa ti ents we re bet we en 1 month-5 ye ars of age. 51% of the ca ses we re ad mit ted to the ER bet we en 16.00-24.00 o'clock. The ma xi mum and the mi ni mum num ber of ad mis si on we re in Ja nu ary (22129 pa ti ents) and in Au gust (12588 pa ti ents). A to tal of 22 585 ca ses (12.6%) with trau ma we re ad mit ted. A to tal of 375 (0.2%) ca ses had the di ag no sis of po iso ning. 10% of the pa ti ents we re ob ser ved in the de part ment. A to...
Arthrogryposis-renal dysfunction-cholestasis syndrome is a rare lethal disorder that involves multipl organ system. It is inherited autosomal recessive and caused by defects in the VPS33B and VIPAR genes. Three cardinal findings of this syndrome are arthrogryposis, renal tubular dysfunction and cholestasis.The other organ involvements including ichthyosis, central nervous system malformation, platelet anomalies, congenital heart defects and severe failure to thrive are sometimes associated with this syndrome. Clinical findings, organ biopsy and mutational analysis can help for diagnosing but there is no curative treatment except supportive care. Several symptoms of this condition are already usually present in the neonatal period: arthrogryposis, neonatal cholestasis, skin lesions, among others. Usually survival is until the first year of life. We present a newborn whose evolution was rapidly fatal.
46,XY pure gonadal dysgenesis (Swyer syndrome) is characterized by normal female genitalia at birth. It usually first becomes apparent in adolescence with delayed puberty and amenorrhea. Rarely, patients can present with spontaneous breast development and/or menstruation. A fifteen-year-old girl presented to our clinic with the complaint of primary amenorrhea. On physical examination, her external genitals were completely female. Breast development and pubic hair were compatible with Tanner stage V. Hormonal evaluation revealed a hypergonadotropic state despite a normal estrogen level. Chromosome analysis revealed a 46,XY karyotype. Pelvic ultrasonography showed small gonads and a normal sized uterus for age. SRY gene expression was confirmed by multiplex polymerase chain reaction. Direct sequencing on genomic DNA did not reveal a mutation in the SRY, SF1 and WT1 genes. After the diagnosis of Swyer syndrome was made, the patient started to have spontaneous menstrual cycles and therefore failed to attend her follow-up visits. After nine months, the patient underwent diagnostic laparoscopy. Frozen examination of multiple biopsies from gonad tissues revealed gonadoblastoma. With this report, we emphasize the importance of performing karyotype analysis, which is diagnostic for Swyer syndrome, in all cases with primary or secondary amenorrhea even in the presence of normal breast development. We also suggest that normal pubertal development in patients with Swyer syndrome may be associated with the presence of a hormonally active tumor.
The literature on neonates with SARS-CoV-2 is mainly concerned with perinatal cases, and scanty data are available about environmentally infected neonates. To fill knowledge gaps on the course and prognosis of neonatal cases, we analyzed 1-year data from the Turkish Neonatal Society in this prospective cohort study of neonates with postnatal transmission. Data from 44 neonatal intensive care units (NICUs), of neonates with positive RT-PCR results at days 5-28 of life, were extracted from the online registry system and analyzed. Of 176 cases, most were term infants with normal birth weight. Fever was the most common symptom (64.2%), followed by feeding intolerance (25.6%), and cough (21.6%). The median length of hospitalization was 9 days, with approximately one quarter of infants receiving some type of ventilatory support. Myocarditis (5.7%) was the most common complication during follow-up. Among the clinical findings, cough (odds ratio [
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