SPR imaging (SPRi) is at the forefront of optical label-free and real-time detection. It offers the possibility of monitoring hundreds of biological interactions simultaneously and from the binding profiles, allows the estimation of the kinetic parameters of the interactions between the immobilised probes and the ligands in solution. We review the current state of development of SPRi technology and its application including commercially available SPRi instruments. Attention is also given to surface chemistries for biochip functionalisation and suitable approaches to improve sensitivity.

No abstract

No abstract

A simplified colloidal lithography protocol (polyelectrolyte monolayer) for Au nanohole fabrication and autocorrelation/FFT analysis of SEM images to disclose hidden short-range periodicities.

No abstract

No abstract

No abstract

No abstract