Introduction. Asymptomatic bacteriuria (ASB),
occurring in 2–11% of pregnancies, is a major predisposition to
the development of pyelonephritis, which is associated with obstetrical complications,
such as preterm labor and low birth weight infants. The aim of this study was to determine
the prevalence of ASB, the antibacterial susceptibilities of the isolated microorganisms and
the associated risk factors in an outpatient clinical setting in Zekai Tahir Burak Women's
Health Education and Research Hospital in Ankara, Turkey.
Material and Methods. Between December 2009 and May 2010,
pregnant women admitted to the antenatal outpatient clinic were included in this study.
The results of a complete urine analysis, midstream urine culture and antibacterial susceptibility were
evaluated. Results. Of the 2011 pregnant women included, 171 had ASB (8.5%).
E. coli was the most frequently isolated microorganism (76.6%), followed by
Klebsiella pneumonia (14.6%). Both microorganisms were highly sensitive to
fosfomycin, sensivity being 99.2% for E. coli and 88% for Klebsiella pneumonia.
Conclusions. In this certain geographical region, we found E. coli
as the most common causative agent of ASB in the obstetric population and it is very
sensitive to fosfomycin. We recommend fosfomycin for ASB in pregnant women
due to its high sensitivity, ease of administration and safety for use in pregnancy.
Background Invasive fungal infections are a major cause of morbidity and mortality in preterm infants. The authors conducted the fi rst prospective, randomised controlled trial of nystatin compared with fl uconazole for the prevention of fungal colonisation and invasive fungal infection in very low birth weight (VLBW) neonates.
Prophylactic S. boulardii supplementation is as effective as nystatin in reducing fungal colonization and invasive fungal infection, more effective in reducing the incidence of clinical sepsis and number of sepsis attacks and has favorable effect on feeding intolerance.
Prophylactic L. reuteri supplementation is as effective as nystatin, and more effective in reducing the incidence of proven sepsis in addition to its favorable effect on feeding intolerance.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.