Several studies have evaluated the possible association between antioxidants vitamins or selenium supplement and the risk of prostate cancer, but the evidence is still inconsistent. We systematically searched PubMed, EMBASE, the Cochrane Library, Science Citation Index Expanded, Chinese biomedicine literature database, and bibliographies of retrieved articles up to January 2009. We included 9 randomized controlled trials with 165,056 participants; methodological quality of included trials was generally high. Meta-analysis showed that no significant effects of supplementation with beta-carotene (RR 0.97, 95% CI 0.90-1.05) (3 trials), vitamin C (RR 0.98, 95% CI 0.91-1.06) (2 trials), vitamin E (RR 0.96, 95% CI 0.85-1.08) (5 trials), and selenium (RR 0.78, 95% CI 0.41-1.48) (2 trials)versus placebo on prostate cancer incidence. The mortality of prostate cancer did not differ significantly by supplement of beta-carotene (RR 1.19, 95% CI 0.87 -1.65) (1 trial), vitamin C (RR 1.45, 95%CI 0.92-2.29) (1 trial), vitamin E (RR 0.85, 95%CI 0.58-1.24) (2 trials), and selenium (RR 2.98, 95% CI 0.12-73.16) (1 trial). Our findings indicate that antioxidant vitamins and selenium supplement did not reduce the incidence and mortality of prostate cancer, these data provide no support for the use of these supplements for the prevention of prostate cancer.
Long-term information of phytoplankton bloom is critical for assessing the processes driving blooms in lakes. A three-decade survey of the phytoplankton blooms was completed for Erhai Lake from 1987 to 2016 with Landsat imagery. A modified three-band model using Landsat broad bands is developed by comparing reflectance data from Landsat imagery to two field datasets. The model is applied to the archived imagery to predict chlorophyll-a (Chl-a). Predicted ln(Chl-a) and observed ln(Chl-a) measurements are significantly correlated (R 2 = 0.70; RMSE = 0.13 µg/L). Bloom maps are generated by identifying Landsat pixels that have Chl-a concentrations larger than 20 µg/L as bloom area. Bloom extent and magnitude are estimated. Our study reveals that algal blooms first occurred in 1996 with a bloom area of 150 km 2 . Bloom occurred frequently from 2002 to 2016, with extreme blooms in 2003, 2013 and 2016. Algal blooms were mostly distributed in the northern and southern part of the lake. The proposed method uses one model for all Landsat images for Erhai Lake and can predict past blooms and extend the record to early years when field data is not available. The bloom extent and magnitude produced in this study can be used as the basis for the understanding of the processes that control the bloom outbreak.
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