The purpose of this study was to analyze brain waves before and after the plant cutting procedure in 34 adult subjects. After plant cutting procedure, RT(Relative power of theta) decreased and RB(Relative power of beta), RMB(Relative power of mid beta), RHB(Relative power of high beta), RST(Ratio of SMR to theta spectrum), RMT(Ratio of mid beta to theta), and RSMT(Ratio of SMR~mid beta to theta) increased, while RA(Relative power of alpha), RLB(Relative power of low beta), and RG(Relative power of gamma) did not change significantly. The decrease in the RT indicator means that the cutting did not cause anxiety as a stable work rather than a high level task. Therefore, it is considered that the cutting activity can be applied to the subjects with low cognitive level such as children, dementia, and intellectual disabilities and those who should avoid the psychological burden due to the performance of the work. The increases in RB, RMB, and RHB indicators mean a state of mental awakening, inducing concentration similar to meditation. Therefore, the activity of cutting can be applied to people who use psychological energy in daily life, psychological confusion, excessive unnecessary thought, troublesome problems. The increases in the RST, RMT, and RSMT indicators mean an increase in concentration. Therefore, it is possible to apply the cutting activity for the purpose of strengthening the attention and intensifying induction. The results of this study are meaningful that it was confirmed that the cutting activity could induce the brain to be awakened by inducing concentration through conscious activities without giving an intellectual anxiety or psychological burden.
This study was designed to examine agro-healing services and programs provided and operated by farms in Korea. The results of the analysis of the agro-healing programs and operation of farms were as follows. The purpose of the operation of farms was to raise productivity by managing farms in a cooperative way through agricultural production, education and healing, and to raise income by processing and selling agricultural products. It was difficult to access farms by public transport and thus visitors had to use their own cars. The size of farms varied. The main resources utilized in the surveyed programs were plants, rural environments and landscapes, and agricultural products. The programs were conducted using resources that were commonly found in rural areas. Facilities on each farm were equipped with facilities (indoor and outdoor learning place, gardens, vegetable gardens, orchards, etc.) and convenience facilities (parking lots, drinking fountains, kiosks, etc.) to support program operation. However, facilities for the handicapped and accommodation facilities were insufficient. The programs operated on each farm utilized agricultural resources, farm produce, and rural resources and were classified into activities such as making, feeling, and growing. The average number of people who operated the family-centered program was 2-3, having qualifications such as welfare horticultural therapists, forest interpreters, experience instructors, and social workers. In addition, they had expertise in medicinal food, dietary life, and social welfare, and they also had essential expertise required to operate programs.
5-Aryl-2,3-dihydroimidazo[2,1-a]isoquinolines were reported to have strong antitumor activity and one of the derivatives such as 5-[4'-(piperidinomethyl)phenyl]-2,3-dihydroimidazo[2,1-a] isoquinoline (1, SDZ 62-434) was found to be more effective than the clinical cytostatic agent edelfosine (2) inin vitro andin vivo assays. Currently SDZ 62-434 is in clinical trials in Europe. The structure-activity relationship studies of SDZ 62-434 showed that compounds with substitution on ring A were less active than the lead compound. Ring B in SDZ 62-434 was essential for the activity because compounds without B ring had no antitumor activity. Among the 3-arylisoquinolin-1-one derivatives, 3-[4'-(piperidonomethyl)phenyl] substituted analog had no antitumor activity but simple phenyl substituted compound, such as4, showed the most potent antitumor activity in various human tumor cell lines.
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