We examined whether alcohol use is associated with antiretroviral therapy (ART) adherence independently of structural and psychosocial factors among 304 male and female ART recipients in ART sites in Tshwane, South Africa. ART adherence was assessed by the CASE Adherence Index. Independent variables were demographic, structural, psycho-social, and alcohol use (AUDIT score) factors. In hierarchical multiple regression, demographic variables (Step 1) explained 4 % of variance in ART adherence (p ≤ 0.01). Variance explained increased to 16 % (p ≤ 0.001) after entering structural variables (Step 2); 19 % (p ≤ 0.001) after entering psychosocial variables (Step 3); and 24 % (p ≤ 0.001) after entering AUDIT score (Step 4). Alcohol use is independently associated with ART adherence.

Background Alcohol and other drug use (AOD) and risky sexual behaviours remain high among adolescents in South Africa and globally. Religiosity influences, mitigates and provides resilience against engaging in risky behaviours among young people but few South African studies have explored potential associations between religiosity, AOD use and risky sex. We report the prevalence of religiosity and association between religiosity and AOD use and risky sexual behaviours among learners in the Western Cape Province, South Africa. Methods Between May and August 2011, a cross sectional survey was conducted among 20 227 learners from 240 public schools randomly selected through a stratified multistage sampling design to determine the prevalence of AOD use and sexual risk behaviours. We performed univariate and multivariate logistic regression analyses to assess the association between religiosity, AOD use and risky sexual behaviours. Results The learners were aged 10–23 years. Almost three quarters (74%) of learners reported high religiosity (defined as attending religious services or activities at least 1–2 times a month). More female than male learners had high religiosity. The prevalence of past 30 day reported alcohol, tobacco and cannabis use was 23%, 19% and 8% respectively. Compared to learners with low religiosity, those with high religiosity were less likely to engage in AOD use: specifically alcohol use, (AOR = 0.86, 95%CI: 0.76–0.97), tobacco use (AOR = 0.76, 95%CI: 0.67–0.87), cannabis use (AOR = 0.57, 95%CI: 0.48–0.68) in the last 30 days. They were also less likely to engage in risky sexual behaviours (AOR = 0.90, 95%CI: 0.81–0.99). Conclusion Religiosity was associated with lower odds of reported AOD use and risky sexual behaviours among learners in the Western Cape. This calls for further exploration on how to incorporate religiosity into AOD use and risky sexual behaviour interventions.

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We sought to (a) replicate and (b) extend (via the addition of alcohol use) Cha et al.'s cross-sectional multi-component model of ART adherence on the relationship between social support, depression, self-efficacy beliefs, and antiretroviral therapy (ART) adherence, among HIV patients in Tshwane, South Africa. Using purposive sampling, 304 male and female ART recipients were recruited. ART adherence was assessed using three manifest indicators: total adherence ratio, the CASE adherence index and 1-month adherence measure. Data were analysed using structural equation modeling. In our replicated model, social support had both direct and indirect relationships with ART adherence, and inclusion of alcohol use improved prediction of ART adherence. Direct and indirect effects of alcohol use on ART adherence emerged: adherence self-efficacy beliefs partially mediated the latter path. Findings highlight the importance of integrating into ART promotion interventions, the reduction of alcohol use, provision of social support, and enhancement of adherence self-efficacy beliefs.

Alcohol consumption is strongly associated with sexual risk behavior and HIV infection in sub-Saharan Africa. This article seeks to explore the role of constructions of masculinity in men’s drinking and sexual risk behavior in drinking venues (bars and taverns) in 2 rural villages of North West Province, South Africa. Ten focus groups were conducted with 58 bar patrons and servers. Four focus groups consisted of female bar patrons, 4 consisted of male bar patrons, and 2 consisted of male bar managers and servers. The participants’ ages ranged from 18 to 43 years, and they were interviewed using focus group discussion guides with open-ended questions. Key themes identified through thematic analysis were (a) men’s high levels of alcohol consumption, (b) men’s tendency to blame women for men’s proneness to risky sex when drinking, (c) men’s sexual objectification of women, and (d) the far-reaching consequences of sexism and violence perpetrated by men. Policies to promote gender equality are needed to ensure that men are more gender-sensitive, engage in more balanced gender relationships, and do not uphold any destructive gender stereotypes.