Coeliac Disease (CD) is an incurable autoimmune condition managed by a therapeutic gluten-free diet for life. European studies suggest that the chronicity of CD, the limitations imposed by the need to follow a permanent restrictive diet and the risk of other associated serious diseases can have a negative impact on health-related quality of life (HRQoL) and psychological well-being. However, studies concerning the psychosocial effects of CD in the UK population are scarce. This cross-sectional survey (N=288) explores the illness perceptions and self-efficacy beliefs of adults with CD in the UK and reports their subjective levels of HRQoL and psychological well-being. Results showed that HRQoL and psychological well-being were reduced with levels being comparable to those found in previous related studies. Participants with weak beliefs in the serious consequences of CD and reduced emotional reactions to the condition had a greater likelihood of having enhanced HRQoL, improved psychological well-being and increased self-efficacy. Strong beliefs in personal control over the condition and a greater perceived understanding of CD were also associated with increased self-efficacy.The results suggest that perceived self-efficacy and illness perceptions could play an important role in informing psychological interventions for individuals with CD.

INR fluctuations may decrease in selected patients with unstable INRs who receive vitamin K supplementation. A study with a larger sample size and longer follow-up period is needed. The results of the present study can help design such a study.

Vitamin K supplementation may decrease variability of INRs in patients with a history of unstable INRs. Further studies are needed in larger populations to clarify the true effects of vitamin K supplementation.

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