Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, Canadian Institutes of Health Research Strategy for Patient Oriented Research through the Ontario SPOR Support Unit, the Ontario Ministry of Health and Long-Term Care, pharmaceutical companies (with major contributions from AstraZeneca [Canada], Sanofi Aventis [France and Canada], Boehringer Ingelheim [Germany amd Canada], Servier, and GlaxoSmithKline), Novartis and King Pharma, and national or local organisations in participating countries.
This study was carried in BSMMU from July 2001 to June 2003. During the study period, 60 pregnant women were studied. Thirty patients were preeclamptic and thirty were normal healthy pregnant women served as control. Serum lipoprotein(a) was found significantly higher in preeclamptic women 56.63±22.6 mg/dl and found within limit in normal healthy pregnant women, 12.89±4.59mg/dl. Result is statistically highly significant (P<0.001). Mean Systolic Blood Pressure was 163.33±29.63 mmHg and 117.00±11.19mmHg in case and control and Diastolic Blood Pressure was 108.53±14.54 mmHg and 76.00±6.87mmHg respectively in case and control group. Result was highly significant as P <0.001. The mean (±SD) serum lipoprotein(a) concentration in normal pregnancies and preeclampsia were found to be 12.91±4.94 and 56.65±22.62. Moderate Proteinuria was found in 77.5% and severe proteinuria in 22.2% cases of preeclampsia respectively. Regardless of mechanism and pathophysiology of preeclampsia, we found high serum level of lipoprotein (a) in preeclampsia patients. These high levels of lipoprotein (a) significantly correlated with blood pressure and proteinuria. DOI: 10.3329/bmrcb.v36i3.7289Bangladesh Med Res Counc Bull 2010; 36: 97-99
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