During the last few years there has been a major change in the perception of childhood asthma management, with more focus on the anti-inflammatory aspects of therapy, the use of inhaled ipratroprium bromide, and decreased home usage of theophylline. Our clinical impression that the management of asthma at our institution has altered in response to these trends prompted us to review our experience with childhood asthma. A random sample of approximately 70 cases was reviewed from admissions to The Hospital for Sick Children during the first 6 months of 1987 and 1990. There was a major reduction in theophylline usage in 1990 accompanied by increased use of ipratroprium and oral corticosteroids. Significantly fewer cases of potentially toxic theophylline serum levels were observed in 1990, suggesting increased awareness of the this drug's narrow therapeutic margin of safety. In 1990, patients tended to be pyrexial and were treated with antibiotics more often. They were also younger, which may explain the higher pulse and respiratory rates observed. Despite these trends toward younger, sicker patients being admitted to the hospital, the length of stay did not increase, and similar numbers needed intensive care. This suggests that the shift in therapeutic modality did not affect hospitalized asthmatic children adversely.
K43In an earlier paper (1) we presented the results of our measurements of the shift of the plasma minimum with uniaxial stress in InSb. We also analysed the results using the energy band structure of deformed InSb as derived by Bir and Pikus (2) and obtained the value of the deformation potential and of the band structure parameters a, R, and S. Unfortunately, due to a numerical error the values of a, R, and S were not reported accurately. In fact, they should have read -87, -0.22, and +8.7 eV, respectively. Since the time of publication of (l), we have made additional measurements of the shift of the plasma minimum with stress in n-type InSb (carrier concentration 1 . 4~1 0~~ ~m -~) .We also added the case of stress along the [llOI axis and reflection at the (100) plane. The results are in general agreement with those obtained previously. Combining all of the measurements we find a value of -41 eV for the deformation potential and a = -87 eV, R = -0.20 eV and S = +4.2 eV. The numerical data quoted above were obtained assuming the effective mass energy gap E to be 0.20 eV at room temperature. One can however follow the argument of Ehrenreich (3) and Brooks (4) and relate the rate of change of the effective mass energy gap with temperature with the deformation potential C and establish the relation g Eg(T) = Eg(O OK) t. 3 d CT , -6 o -1where d is the coefficient of linear expansion (4.7xlO K (5)). Assuming E (0 OK) =O. 23 evandusingthe' expressions obtained in (l), one can determine a self-consistent value for the deformation potential. Following this procedure we obtain C = -25 eV. This value corresponds to ( a E /aP), = 5.4~10 1) Present address:
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