CHLT in adolescents and young adults is performed increasingly for failed palliation of single ventricle congenital heart disease. 1 Although longitudinal studies have reported equivalent post-transplant survival compared with HT alone, post-operative morbidity, including the prevalence of AKI and CKD, has yet to be characterized sufficiently. 2 Given the highly morbid nature of CHLT, this remains an important area of study. 1 Although studies in the CHLT population are rare, 1 isolated heart and liver transplants are independently associated with AKI and CKD development. 3 AKI occurs in up to 72% of pediatric HT
Introduction:
Gaps in insurance coverage have been associated with diminished access to health care for children with chronic illness. Continuity of coverage is associated with improved long-term clinical outcomes among adolescent heart transplant (HT) recipients, but the relationship between insurance status and post-transplant outcomes has not been described across all pediatric HT recipients.
Hypothesis:
HT recipients with changes in insurance status will have worse outcomes as opposed to those with continuous coverage.
Methods:
We queried the United Network for Organ Sharing (UNOS) registry for patients age 0-18 receiving isolated HT or heart re-transplant between 2006 and 2019 and included them in the analysis if they survived at least one year post-transplant. Patients were categorized by insurance coverage at wait listing, HT, and one year follow-up. Cox proportional hazards models were used to characterize the association between coverage pattern and long-term patient survival.
Results:
Among the 3,247 patients in the analysis, insurance coverage patterns included continuous private (37%), continuous public (46%), gain of private (6%), and loss of private (11%). Patients who had continuous public insurance were more likely to be Black or Hispanic, adolescent, and require ICU care. In a multivariate Cox model, continuous public insurance was associated with increased mortality risk (HR = 1.46, P = 0.014), while loss of private insurance trended towards increased risk (HR = 1.14, P = 0.014). Figure 1 illustrates Kaplan-Meier conditional survival curves according to insurance trajectory. Multivariate sub-group analysis by Black race demonstrated no differences in outcomes by coverage pattern.
Conclusions:
In comparison to those with continuous private insurance, having continuous public insurance is associated with higher risk of adverse outcomes in pediatric HT recipients, but it does not account for disparate outcomes in Black patients.
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