Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and delivery strategies, which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field. A wide variety of natural and modified peptides have been obtained and studied, covering multiple therapeutic areas. This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications. We also discuss the value and challenges associated with future developments in therapeutic peptides.

Aqueous zinc‐ion batteries (ZIBs) are considered to be a promising candidate for flexible energy storage devices due to their high safety and low cost. However, the scalable assembly of flexible ZIBs is still a challenge. Here, a scalable assembly strategy is developed to fabricate flexible ZIBs with an ultrathin all‐in‐one structure by combining blade coating with a rolling assembly process. Such a unique all‐in‐one integrated structure can effectively avoid the relative displacement or detachment between neighboring components to ensure continuous and effective ion‐ and/or loading‐transfer capacity under external deformation, resulting in excellent structural and electrochemical stability. Furthermore, the ultrathin all‐in‐one ZIBs can be tailored and edited controllably into desired shapes and structures, further extending their editable, stretchable, and shape‐customized functions. In addition, the ultrathin all‐in‐one ZIBs display the ability to integrate with perovskite solar cells to achieve an energy harvesting and storage integrated system. These enlighten a broad area of flexible ZIBs to be compatible with highly flexible and wearable electronics. The scaling‐up assembly strategy provides a route to design other ultrathin all‐in‐one energy storage devices with stretchable, editable, and customizable behaviors.

Our study of a northern China sample of CEOs, middle managers and frontline employees matched across 114 firms investigates the relationship between a high commitment work system and firm performance from an organizational perspective by considering the mediating role of collective psychological capital (PsyCap) and the moderating role of environmental uncertainty. The effect of a high commitment work system on firm performance was fully mediated by collective PsyCap, while environmental uncertainty moderated the effect of collective PsyCap on firm performance such that firm performance was stronger when environmental uncertainty was higher. We contribute to the developing body of work using collective PsyCap as a mediator for the high commitment work system–performance relationship at the organizational level. Our selection of environmental uncertainty as a moderator responds to the call for research on potential moderators and more consideration of context. We discuss our study's managerial implications and limitations.

No abstract