The self-healing property of metallogels resembles the innate self-healing of plant and animal biomaterials, making metallogels potential candidates for detailed studies. Tetrazoles with diverse coordination abilities and extensive H-bond formation capabilities may be able to be used as ligands to generate metallogels. In this report, four metallogels (M1G6Cl, M2G6Cl, M1G6NO 3 , and M3G6NO 3 ) based on different lanthanoids and functionalized with di­(1H-tetrazole-5-yl)­methane (H 2 G6) are designed and fabricated. All the metallogels are well characterized by different spectroscopic methods. The mechanical strengths of the metallogels are determined by rheology, and FE-SEM images reveal diverse needle-like morphologies of the metallogels after the formation of ordered self-assembled networks. All the metallogels are found to be photoluminescent in nature, with quantum yields falling in the range 0.75–0.12. The emissive nature of the gels is utilized to perform invisible photopatterning experiments, which show the potential of these metallogels to be used in confidential image or writing applications. Furthermore, the crystallization of the M3G6NO 3 metallogel in a confined gel space provides a pathway of elucidating its structure, which can be used to help predict the kinds of noncovalent interactions involved in the ordered self-assembly process. The self-healing nature of the M1G6Cl metallogels makes them the most interesting among all the gels and is further explored by the rhodamine dye-doped approach. Moreover, the low molecular weight, self-healable M1G6Cl metallogels act as unique soft materials for water purification by absorbing 98% Rhodamine B dye from water in 24 h.

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With the enormous progress in ruthenium complexes as promising anticancer agents after the entry of KP1019, KP1339, and NAMI-A in clinical trials, herein three arene ruthenium­(II) NSAID (nonsteroidal anti-inflammatory drugs) complexes viz. [Ru­(η6-p-cymene)­(mef)­Cl] (1), [Ru­(η6-p-cymene)­(flu)­Cl] (2), and [Ru­(η6-p-cymene)­(dif)­Cl] (3) are synthesized, characterized, and reported. Density functional theory (DFT) calculations were performed in support of the obtained experimental results by computing the equilibrium geometries, reactions pathways, relative Gibbs free energy, stability, and reactions barriers of the complexes. The present theoretical study shows that all the proposed structures of the complexes are energetically stable and favorable, and the results obtained are in close accordance with the experiment. Further, the in vitro cytotoxicity of the complexes was explored through MTT assay on MCF-7, Hela, A549, and HEK cell lines. It was found the complex 1 and 2 are significantly cytotoxic toward the MCF-7 cell line. These complexes have also shown a strong affinity toward CT-DNA and proteins (HSA and BSA) as analyzed through spectroscopic techniques. Further investigation of the mechanism of cell death of selected complexes was carried out by various staining, flow cytometry, and gene expression analysis obtained by RT-PCR.

Visible-light-driven photoreactions using metal complexes as catalysts are currently a research hotspot in terms of the development of environmentally friendly sustainable processes. To develop potential copper-based photocatalysts, a Mannich base ligand, namely, 2,4-dichloro-6-((4-(2-hydroxyethyl) piperazin-1-yl)methyl)phenol (H 2 L), has been synthesized and characterized.Two copper complexes [Cu (HL 1 )] ( 1) and [Cu (HL 2 )] (2) have been obtained from H 2 L, where the ligand undergoes an unprecedented transformation plausibly via oxidation of piperazine ring to ketone, subsequent oxidation of enol and nucleophilic attack of methanol followed by hydrolysis of amide bond, resulting piperazine ring cleavage. Under the irradiation of visible light, these catalysts can oxidize primary alcohols into corresponding aldehydes with very good conversion and high selectivity in the presence of molecular oxygen. The photocatalysts could be recovered almost quantitatively after completion of the catalytic cycle and recycled at least four times without much depreciation of catalytic activity. A plausible mechanistic pathway for alcohol oxidation has been explored through electrospray ionization mass spectrometry (ESI-MS) spectrometric, cyclic voltammetry, UV-vis, and computational study.

Here we report the synthesis of a thermally and chemically robust novel ionic porous organic polymer (iPOP-ANT) with exchangeable Cl- ions by a one-step condensation reaction. The polymer works as...