Patient: Male, 70Final Diagnosis: Cardiogenic shockSymptoms: Chest discomfort and intermittent palpitationsMedication: AmiodaroneClinical Procedure: IntubationSpecialty: CardiologyObjective:Unusual clinical courseBackground:Amiodarone is frequently used in emergency departments for treatment of arrhythmias. Incidence of several amiodarone-related adverse events is unknown. The literature is sparse for potentially life-threatening adverse effects of amiodarone.Case Report:We present a case of a male patient who presented with chest discomfort and rapid atrial fibrillation. He was known to have paroxysmal atrial fibrillation, which did not respond to initial beta-blocker treatment. The second-line drug amiodarone was given to the patient for rate control. He developed severe hypotension related to amiodarone and required inotropic support along with rapid-sequence intubation.Conclusions:Intravenous amiodarone can cause severe and refractory hypotension.
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