BACKGROUNDThe application of controlled levels of negative pressure has been shown to accelerate debridement and promote healing in many different types of wounds. The optimum level of negative pressure appears to be around 125 mmHg below ambient and there is evidence that this is most effective if applied in a cyclical fashion of five minutes on and two minutes off. It is believed that the negative pressure assists with removal of interstitial fluid, decreasing localised oedema and increasing blood flow. This in turn de creases tissue bacterial levels. Additionally, mechanical deformation of cells is thought to result in protein and matrix molecule synthesis, which increases the rate of cell proliferation. Despite the significant costs involved, the technique is said to compare favourably in financial terms with conventional treatments in the management of difficult to heal wounds.
BACKGROUNDPerforated peptic ulcer or ileal ulcer is a serious complication of ulcers with potential risk of grave complications. There is paucity of published reports on perforated peptic ulcer disease and ileal ulcer disease in our local environment. This study was conducted to evaluate the clinical presentation, management and outcome of patients with both ulcer perforations in our setting and to identify predictors of outcome of these patients.
BACKGROUNDAcute appendicitis is one of the most common cause of acute abdomen and surgical emergencies. Failure to make an early diagnosis converts acute appendicitis to perforated appendicitis, a disease with potential complications including wound infection, pelvic abscess, portal pyaemia, septicaemia, and death. Our objective of the study is whether proper clinical examination along with clinical scoring pattern coupled with cost-effective radiological investigations help to improve the diagnosis as confirmed later by operative and histopathological examination to recognise patients without appendicitis to have an alternative diagnosis in these patients with right lower quadrant of abdomen.
BACKGROUNDWhile in general practice chronic non-specific abdominal complaints are common; there is insufficient data on the clinical course and the management of these complaints. Aim of this study was to present a primary care based profile of these chronic complaints including health care involvement, health status and clinical course. [1], [2]
BACKGROUNDAlthough, appendicectomy is the most commonly done emergency surgery, still its diagnosis remains an enigmatic challenge with persisting high rate of negative explorations. The objective of the study was to evaluate the role of accuracy of WBC measurement in the diagnosis of acute appendicitis and to reduce the morbidity by avoiding negative explorations.
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