Purpose: The ion collection efficiency of vented ionization chambers has been investigated in an ultrahigh dose-per-pulse (DPP) electron beam. The role of the chamber design and the electric field strength in the sensitive air volume have been evaluated. Methods: An advanced Markus chamber and three specially designed parallel plate air-filled ionization chambers (EWC: End Window Chamber) with varying electrode distance of 0.5, 1 and 2 mm have been investigated. Their ion collection efficiencies were determined experimentally using two methods: extrapolation of Jaffé plots and comparison against a DPP independent reference detector. The latter was achieved by calibrating a current transformer against alanine dosimeters. All measurements were performed in a 24 MeV electron beam with DPP values between 0.01 Gy and 3 Gy. Additionally, the numerical approach introduced by Gotz et al. was implemented taking into account space charge effects at these ultra-high DPPs. The method has been extended to obtain time-resolved and position-dependent electric field distortions within the air cavity. Accepted Article This article is protected by copyright. All rights reserved Results: The ion collection efficiency of the investigated ionization chambers drops significantly in the ultra-high DPP range. The extent of this drop is dependent on the electrode distance, the applied chamber voltage and thus the field strength in the sensitive air volume. For the Advanced Markus chamber, a good agreement between the experimental, numerical and the results of Petersson et al. could be shown. Using the three EWCs with different electrode spacing, an improvement of the ion collection efficiency and a reduction of the polarity effect with decreasing electrode distance could be demonstrated. Furthermore, the results revealed that the determination of the ion collection efficiency from the Jaffé plots and therefore also from two-voltage method typically underestimate the ion collection efficiency in the region of high dose-per-pulse (3 mGy to 130 mGy) and overestimate the ion collection efficiency at ultra-high dose-per-pulse (> 1 Gy per pulse). Conclusions: In this work, the ion collection efficiency determined with different methods and ionization chambers have been compared and discussed. As expected, an increase of the electric field in the ionization chamber, either by applying a higher bias voltage or a reduction of the electrode distance, improves the ion collection efficiency and also reduces the polarity effect. For the Advanced Markus chamber, the experimental results obtained by comparison against a reference agree well with the numerical solution. Based on these results, it seems possible to keep the recombination loss less than or equal to 5% up to a dose-per-pulse of 3 Gy with an appropriately designed ionization chamber, which corresponds to the level accepted in conventional radiotherapy dosimetry protocols.
UHDpulse -Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates is a recently started European Joint Research Project with the aim to develop and improve dosimetry standards for FLASH radiotherapy, very high energy electron (VHEE) radiotherapy and laser-driven medical accelerators. This paper gives a short overview about the current state of developments of radiotherapy with FLASH electrons and protons, very high energy electrons as well as laser-driven particles and the related challenges in dosimetry due to the ultra-high dose rate during the short radiation pulses. We summarize the objectives and plans of the UHDpulse project and present the 16 participating partners.
PurposeDosimetric properties of the new microSilicon diode detector (60023) have been studied with focus on application in small‐field dosimetry. The influences of the dimensions of the sensitive volume and the density of the epoxy layer surrounding the silicon chip of microSilicon have been quantified and compared to its predecessor (Diode E 60017) and the microDiamond (60019, all PTW‐Freiburg, Germany).MethodsDose linearity has been studied in the range from 0.01 to 8.55 Gy and dose‐per‐pulse dependence from 0.13 to 0.86 mGy/pulse. The effective point of measurement (EPOM) was determined by comparing measured percentage depth dose curves with a reference curve (Roos chamber). Output ratios were measured for nominal field sizes from 0.5 × 0.5 cm2 to 4 × 4 cm2. The corresponding small‐field output correction factors, k, were derived with a plastic scintillation detector as reference. The lateral dose–response function, K(x), was determined using a slit beam geometry.ResultsMicroSilicon shows linear dose response (R 2 = 1.000) in both low and high dose range up to 8.55 Gy with deviations of only up to 1% within the dose‐per‐pulse values investigated. The EPOM was found to lie (0.7 ± 0.2) mm below the front detector’s surface. The derived k for microSilicon (0.960 at s eff = 0.55 cm) is similar to that of microDiamond (0.956), while Diode E requires larger corrections (0.929). This improved behavior of microSilicon in small‐fields is reflected in the slightly wider K(x) compared to Diode E. Furthermore, the amplitude of the negative values in K(x) at the borders of the sensitive volume has been reduced.ConclusionsCompared to its predecessor, microSilicon shows improved dosimetric behavior with higher sensitivity and smaller dose‐per‐pulse dependence. Profile measurements demonstrated that microSilicon causes less perturbation in off‐axis measurements. It is especially suitable for the applications in small‐field output factors and profile measurements.
The aim of this study is the experimental and Monte Carlo-based determination of small field correction factors for the unshielded silicon detector microSilicon for a standard linear accelerator as well as the Cyberknife System. In addition, a detailed Monte Carlo analysis has been performed by modifying the detector models stepwise to study the influences of the detector's components. Methods: Small field output correction factors have been determined for the new unshielded silicon diode detector, microSilicon (type 60023, PTW Freiburg, Germany) as well as for the predecessors Diode E (type 60017, PTW Freiburg, Germany) and Diode SRS (type 60018, PTW Freiburg, Germany) for a Varian TrueBeam linear accelerator at 6 MV and a Cyberknife system. For the experimental determination, an Exradin W1 scintillation detector (Standard Imaging, Middleton, USA) has been used as reference. The Monte Carlo simulations have been performed with EGSnrc and phase space files from IAEA as well as detector models according to manufacturer blueprints. To investigate the influence of the detector's components, the detector models have been modified stepwise. Results: The correction factors for the smallest field size investigated at the TrueBeam linear accelerator (equivalent dosimetric square field side length S clin = 6.3 mm) are 0.983 and 0.939 for the microSilicon and Diode E, respectively. At the Cyberknife system, the correction factors of the microSilicon are 0.967 at the smallest 5-mm collimator compared to 0.928 for the Diode SRS. Monte Carlo simulations show comparable results from the measurements and literature. Conclusion: The microSilicon (type 60023) detector requires less correction than its predecessors, Diode E (type 60017) and Diode SRS (type 60018). The detector housing has been demonstrated to cause the largest perturbation, mainly due to the enhanced density of the epoxy encapsulation surrounding the silicon chip. This density has been rendered more water equivalent in case of the microSilicon detector to minimize the associated perturbation. The sensitive volume itself has been shown not to cause observable field size-dependent perturbation except for the volume-averaging effect, where the slightly larger diameter of the sensitive volume of the microSilicon (1.5 mm) is still small at the smallest field size investigated with corrections <2%. The new microSilicon fulfils the 5% correction limit recommended by the TRS 483 for output factor measurements at all conditions investigated in this work.
Background: Conventional air ionization chambers (ICs) exhibit ion recombination correction factors that deviate substantially from unity when irradiated with dose per pulse magnitudes higher than those used in conventional radiotherapy. This fact makes these devices unsuitable for the dosimetric characterization of beams in ultra-high dose per pulse as used for FLASH radiotherapy. Purpose: We present the design, development, and characterization of an ultrathin parallel plate IC that can be used in ultra-high dose rate (UHDR) deliveries with minimal recombination. Methods: The charge collection efficiency (CCE) of parallel plate ICs was modeled through a numerical solution of the coupled differential equations governing the transport of charged carriers produced by ionizing radiation. It was used to find out the optimal parameters for the purpose of designing an IC capable of exhibiting a linear response with dose (deviation less than 1%) up to 10 Gy per pulse at 4 μ s pulse duration. As a proof of concept, two vented parallel plate IC prototypes have been built and tested in different ultra-high pulse dose rate electron beams. Results: It has been found that by reducing the distance between electrodes to a value of 0.25 mm it is possible to extend the dose rate operating range of parallel plate ICs to ultra-high dose per pulse range, at standard voltage of clinical grade electrometers,well into several Gy per pulse.The two IC prototypes exhibit behavior as predicted by the numerical simulation. One of the so-called ultrathin parallel plate ionization chamber (UTIC) prototypes was able to measure up to 10 Gy per pulse, 4 μ s pulse duration, operated at 300 V with no significant deviation from linearity within the uncertainties (ElectronFlash Linac, SIT). The other prototype was tested up to 5.4 Gy per pulse, 2.5 μ s pulse duration, operated at 250 V with CCE higher than 98.6% (Metrological Electron Accelerator Facility, MELAF at Physikalisch-Technische Bundesanstalt, PTB). Conclusions: This work demonstrates the ability to extend the dose rate operating range of ICs to ultra-high dose per pulse range by reducing the spacing between electrodes. The results show that UTICs are suitable for measurement in UHDR electron beams.
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