BackgroundFaculty members face demands such as research, outreach programs, and management activities. Such demands may expose faculty to burnout. Burnout affects the physical, psychological and social health of faculty members, but it is still unclear how it affects their quality of life. We aimed to assess the impact of burnout on the quality of life (QoL) of faculty members from different fields of knowledge.MethodsCross-sectional study using validated tools for measuring burnout and QoL (Oldenburg Burnout Inventory–OLBI and World Health Organization Quality of Life-Abbreviated version–WHOQOL-Bref) in a sample of 366 faculty members from a public university. Scores were analyzed using Student’s t-test, analysis of variance (ANOVA), binary logistic regression, and structural equation modeling (SEM).ResultsMore than a third of the faculty members (n = 127; 36.6%) suffered from burnout. Men had higher scores of quality of life than women in the physical health (p = 0.001; d<0.5), psychological (p = 0.001; d<0.5) and social relationships (p = 0.048; d<0.5) domains. Women were more exhausted than men (p = 0.001; d<0.5). Faculty members’ perception of quality of life and burnout did not differ according to their field of knowledge (p>0.05). Participants who felt tired before arriving at work were less likely to report good quality of life (OR = 0.46; 95% CI = 0.21–0.99). Faculty members who stated they needed more time to relax after work were less likely to be satisfied with their health (OR = 0.20; 95% CI = 0.10–0.40). Burnout showed a negative association with quality of life (λ = 0.87; p < 0,001; df = 8).ConclusionsBurnout negatively affects faculty members’ quality of life, regardless of their field of knowledge. Our results suggest the implementation of programs and actions to prevent burnout to faculty members, especially to women, as their quality of life may affect the quality of the education provided.

BackgroundRaine syndrome (RS) is a rare autosomal recessive bone dysplasia typified by osteosclerosis and dysmorphic facies due to FAM20C mutations. Initially reported as lethal in infancy, survival is possible into adulthood. We describe the molecular analysis and clinical phenotypes of five individuals from two consanguineous Brazilian families with attenuated Raine Syndrome with previously unreported features.MethodsThe medical and dental clinical records were reviewed. Extracted deciduous and permanent teeth as well as oral soft tissues were analysed. Whole exome sequencing was undertaken and FAM20C cDNA sequenced in family 1.ResultsFamily 1 included 3 siblings with hypoplastic Amelogenesis Imperfecta (AI) (inherited abnormal dental enamel formation). Mild facial dysmorphism was noted in the absence of other obvious skeletal or growth abnormalities. A mild hypophosphataemia and soft tissue ectopic mineralization were present. A homozygous FAM20C donor splice site mutation (c.784 + 5 g > c) was identified which led to abnormal cDNA sequence. Family 2 included 2 siblings with hypoplastic AI and tooth dentine abnormalities as part of a more obvious syndrome with facial dysmorphism. There was hypophosphataemia, soft tissue ectopic mineralization, but no osteosclerosis. A homozygous missense mutation in FAM20C (c.1487C > T; p.P496L) was identified.ConclusionsThe clinical phenotype of non-lethal Raine Syndrome is more variable, including between affected siblings, than previously described and an adverse impact on bone growth and health may not be a prominent feature. By contrast, a profound failure of dental enamel formation leading to a distinctive hypoplastic AI in all teeth should alert clinicians to the possibility of FAM20C mutations.Electronic supplementary materialThe online version of this article (doi:10.1186/s12881-015-0154-5) contains supplementary material, which is available to authorized users.

Physical training associated with blood flow restriction increased cephalic vein diameters in both groups and was effective in increasing the diameter of the radial artery; however, it did not demonstrate superiority over the exercise group protocol without blood flow restriction.

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Este estudo propôs-se a investigar um modelo em que as variáveis satisfação no trabalho e percepção de suporte organizacional consistem em preditoras da síndrome de burnout em profissionais de enfermagem. A amostra do estudo foi composta por 339 trabalhadores de enfermagem de um hospital universitário, que responderam um instrumento composto por dados sócio-demográficos e por escalas validadas das variáveis estudadas. Após realizadas as análises de regressão múltipla (método stepwise), constatou-se que os maiores percentuais de explicação para as três dimensões da síndrome de burnout foram atribuídos às variáveis satisfação com a natureza do trabalho e à percepção de suporte organizacional. Os resultados evidenciam a importância da natureza do trabalho e do apoio organizacional para esses profissionais e alertam para que as organizações de saúde lhes estabeleçam estratégias de valorização. A prevenção desta síndrome é fundamental para a garantia de um atendimento de qualidade aos usuários dos serviços de saúde. Palavras-chave: Stress ocupacional. Satisfação no trabalho. Condições de trabalho.

The main organic contaminants in municipal wastewater are proteins, polysaccharides, and lipids, which must be hydrolyzed to smaller units. A high concentration of oil and grease in wastewater affects biological wastewater treatment processes by forming a layer on the water surface, which decreased the oxygen transfer rate into the aerobic process. Microbial proteases, lipases, amylases, and celullases should play essential roles in the biological wastewater treatment process. The present study aimed to isolate lipase- and other hydrolytic enzyme-producing microorganisms and assess their degradation capabilities of fat and oil wastewater in the laboratory. We also evaluated microbial interactions as an approach to enhance lipolytic activity. We place emphasis on lipase activity because oil and grease are not only environmental pollutants, but also form an undesirable tough crust on pipes of sewage treatment plants. Thirty-five lipolytic microorganisms from sewage were identified and assessed for hydrolytic enzyme profiles. Lipases were characterized in detail by quantification, chain length affinity, and optimal conditions for activity. The good stability of isolated lipases in the presence of chemical agents, thermal stability, wide range of pH activity and tolerance, and affinity for different lengths of ester chains indicates that some of these enzymes may be good candidates for the hydrolysis of organic compounds present in wastewater. A combination of enzymes and fermenting bacteria may facilitate the complete hydrolysis of triglycerides, proteins, and lingo-cellulose that normally occur in the wastes of industrial processes. This study identifies enzymes and microbial mixtures capable of digesting natural polymeric materials for facilitating the sewage cleaning process.

DIABETES GESTACIONAL E NUTRIÇÃO | 95Rev. Nutr., Campinas, 23 (1) R E S U M OTrata-se de uma revisão da literatura científica sobre a terapia nutricional no Diabetes Mellitus Gestacional, sem restrição de data e com fontes primárias indexadas nas bases de dados SciELO, PubMed, Medline. Os resultados desta revisão apontam a intervenção nutricional como uma importante aliada no controle do Diabetes Mellitus Gestacional, trazendo potenciais benefícios à saúde materno-fetal. Na avaliação do estado nutricional materno devem ser empregados os indicadores antropométricos, dietéticos, bioquímicos, clínicos e funcional. Neste sentido, a avaliação dietética deve ser detalhada, com atenção para o fracionamento e composição das refeições, e grupos de alimentos presentes. No planejamento nutricional a distribuição de macronutrientes em relação ao consumo energético diário deve ser 45-65% de carboidratos, 15-20% de proteínas e 20-35% de lipídeos. Quanto a recomendação dos edulcorantes, são liberados para gestantes acesulfame K, aspartame, neotame, sacarina e sucralose. A atividade física também deve fazer parte da estratégia de tratamento do Diabetes Mellitus Gestacional, embora o impacto do exercício nas complicações neonatais ainda mereça ser rigorosamente testado. Ademais, estudos associam a habilidade de aconselhamento nutricional com a melhorara na adesão ao cuidado nutricional. Diante desses achados, para sucesso no controle do DMG são necessários: a participação da equipe inter e multidisciplinar, o cuidado pré-natal precoce, com assistência nutricional oportuna e a garantia da assistência de qualidade ao longo da gestação. Termos de indexação:Cuidado pré-natal. Diabetes gestacional. Gestante. Nutrição. A B S T R A C T

Well-being at work is based on Positive Psychology, and is defined as a psychological state with positive affective links towards work and also towards the organisation. The purpose of this study was to look at the degree of well-being at work among nursing professionals who work at a University hospital and also identify differences between occupational categories and types of work contracts. The sample was made up of 340 professionals who answered valid scales of the following constructs: Work Satisfaction, Involvement with Work and Affective Organisational Commitment. For the analysis of the data we used SPSS, version 12, for descriptive statistics, and also for testing differences between means. The results showed an average level of well-being in the workplace and also differences between professional categories and work regime, when it comes to satisfaction with salaries and promotions, which can have a reflection in the quality of service provided to the patients of this University hospital. Evaluación del bienestar en el trabajo entre los profesionales de enfermería de un hospital universitarioBienestar en el trabajo se apoya en la Psicología Positiva, siendo definido como un estado psicológico compuesto por vínculos afectivos positivos con el trabajo y con la organización.Este estudio tuvo por objetivo conocer el nivel de bienestar en el trabajo de profesionales de enfermería que actúan en un hospital universitario e identificar diferencias entre categorías ocupacionales y tipos de contrato de trabajo. La muestra fue compuesta por 340 profesionales que contestaron escalas válidas de los constructos: Satisfacción en el Trabajo, Envolvimiento con el Trabajo y Comprometimiento Organizacional Afectivo. Para análisis de los datos se utilizó el programa SPSS, versión 12, para efectuar estadísticas descriptivas y testes de diferencia entre medias. Los resultados indicaron nivel medio de bienestar en el trabajo y diferencias entre las categorías profesionales y régimen de contratación en cuanto a la satisfacción con salario y promociones, lo que puede reflejar en la calidad del servicio prestado a los pacientes del hospital universitario.