BACKGROUND: Liver abscess is a common problem in lower socioeconomic group in India. Both types (Amoebic and pyogenic) of liver abscesses are important cause of morbidity and mortality in India. AIM: To observe the clinical features, biochemical and radiological abnormality, microbiological etiologies, and management outcomes in patients with liver abscess. MATERIALS AND METHODS: An open prospective study was conducted in the Department of Medicine, GR Medical College and JA Group of Hospitals, Gwalior from November 2009 to October 2011.The patients presenting with Liver abscess on ultrasonography (USG) were included. A detailed history, clinical examination, and laboratory profile of the patients were recorded. Radiological examination was also done to observe any pulmonary complication along with USG to observe size, site, number, echogenicity and other abnormalities. Effects of antibiotic and surgical intervention (USG guided aspiration or pigtail insertion) were also studied. RESULTS: A total of 104 patients were included in the study, out of which 52 were males. Most of them were from lower socioeconomic class (61.19%) and alcoholic (68.62%). Most patients presented with fever and abdominal pain. Most of the patients in amoebic liver abscess (ALA) group were of <40 years of age and in pyogenic liver abscess (PLA) >40 years of age. Liver abscess was mostly present in right lobe (65.67%) and single (59.70%). Etiology of abscess was 58.2% amoebic, 41.8% pyogenic. Diabetes mellitus and cholelithiasis were main inclining factors in case of liver abscess. Most common laboratory finding was abnormal alkaline phosphatase. All patients with ALA & 26 out of 29 patients with PLA improved with medical therapy. CONCLUSIONS: The most common presentation for liver abscess was male, alcoholic of low socioeconomic class having right lobe single abscess.
Xanthomas are often a manifestation of underlying lipid abnormalities. A 50-year-old male presented to our hospital with the lesions of multiple tuberous xanthomas all over the body. Routine investigations and systemic examination were normal. Lipid profile was within normal range and serum protein electrophoresis showed normal pattern. Histopathology from a nodular lesion showed collection of foamy macrophages in the dermis. We present a case of normolipemic tuberous xanthomas, which is an uncommon occurrence.
Background: High suicide rate is reported in India, and poisoning seems to be main cause in majority of these suicide cases. An enhanced rate is seen in poisoning by hair dye, and in few places, it comprises a huge part of the poisoning cases. Objective: To study the clinical profile, electrocardiographic (ECG) changes, and biochemical parameters of patients presenting with hair dye poisoning.
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