Oral health represents an essential component in the quality of life of people, being a determinant factor in general health since it may affect the risk of suffering other conditions, such as chronic diseases. Oral diseases have become one of the main public health problems, where dental caries is the condition that most affects oral health worldwide, occurring in about 90% of the global population. This condition has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused depending on the consumption of certain nutritional elements interacting simultaneously with different factors, such as socioeconomic factors. Based on this problem, an analysis of a set of 189 dietary and demographic determinants is performed in this work, in order to find the relationship between these factors and the oral situation of a set of subjects. The oral situation refers to the presence and absence/restorations of caries. The methodology is performed constructing a dense artificial neural network (ANN), as a computer-aided diagnosis tool, looking for a generalized model that allows for classifying subjects. As validation, the classification model was evaluated through a statistical analysis based on a cross validation, calculating the accuracy, loss function, receiving operating characteristic (ROC) curve and area under the curve (AUC) parameters. The results obtained were statistically significant, obtaining an accuracy ≃ 0.69 and AUC values of 0.69 and 0.75. Based on these results, it is possible to conclude that the classification model developed through the deep ANN is able to classify subjects with absence of caries from subjects with presence or restorations with high accuracy, according to their demographic and dietary factors.
Depression is a mental disorder characterized by recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, in addition to fatigue, causing inability to perform daily activities, which leads to a loss of quality of life. To monitor depression (unipolar and bipolar patients), traditional methods rely on reports from patients; nevertheless, bias is commonly present in them. To overcome this problem, Ecological Momentary Assessment (EMA) reports have been widely used, which include data of the behavior, feelings and other types of activities recorded almost in real time through the use of portable devices and smartphones containing motion sensors. In this work a methodology was proposed to detect depressive subjects from control subjects based in the data of their motor activity, recorded by a wearable device, obtained from the “Depresjon” database. From the motor activity signals, the extraction of statistical features was carried out to subsequently feed a random forest classifier. Results show a sensitivity value of 0.867, referring that those subjects with presence of depression have a degree of 86.7% of being correctly classified, while the specificity shows a value of 0.919, referring that those subjects with absence of depression have a degree of 91.9% of being classified with a correct response, using the motor activity signal provided from the wearable device. Based on these results, it is concluded that the motor activity allows distinguishing between the two classes, providing a preliminary and automated tool to specialists for the diagnosis of depression.
Depression is a mental disorder manifested through a set of psychological and physical symptoms, such as the presence of sadness, apathy, hopelessness and irritability, among others. According to the World Health Organization (WHO), depression is affecting more than 300 million people worldwide, presenting a prevalence between 3 and 21%. One of the main problems of this high prevalence is the incorrect classification of patients, since many cases are false positive and false negative diagnoses. In this work it is proposed the study of the behavior of five different classification techniques, random forest (RF), conditional inference trees (cTree), K-nearest neighbor (K-NN), support vector machine (SVM) and Naïve Bayes, to identify depressive states through the motor activity of patients contained in the Depresjon dataset. The activity of this dataset is acquired through the smart watch "Actigraph", based on actigraphy. The evaluation of these classification techniques is finally performed in terms of sensitivity, specificity, the receiver operating characteristic (ROC) curve and area under the curve (AUC), to know their performance to automatically detect depressive patients. The results shown values of sensitivity, specificity and AUC, statistically significant, specially for the RF method, which presents sensitivity = 0.8148, specificity = 0.8158 and AUC = 0.8314. Therefore, it is concluded that these classifiers are able to distinguish patients with depression from controls, based on their motor activity, allowing the development of a non-invasive diagnosis tool to support specialists in the correct diagnosis of depression.
Depression is a mental disorder which typically includes recurrent sadness and loss of interest in the enjoyment of the positive aspects of life, and in severe cases fatigue, causing inability to perform daily activities, leading to a progressive loss of quality of life. Monitoring depression (unipolar and bipolar patients) stats relays on traditional method reports from patients; however, bias is commonly present, given the patients’ interpretation of the experiences. Nevertheless, to overcome this problem, Ecological Momentary Assessment (EMA) reports have been proposed and widely used. These reports includes data of the behaviour, feelings, and other type of activities recorded almost in real time using different types of portable devices, which nowadays include smartphones and other wearables such as smartwatches. In this study is proposed a methodology to detect depressive patients with the motion data generated by patient activity, recorded with a smartband, obtained from the “Depresjon” database. Using this signal as information source, a feature extraction approach of statistical features, in time and spectral evolution of the signal, is done. Subsequently, a clever feature selection with a genetic algorithm approach is done to reduce the amount of information required to give a fast noninvasive diagnostic. Results show that the feature extraction approach can achieve a value of 0.734 of area under the curve (AUC), and after applying feature selection approach, a model comprised by two features from the motion signal can achieve a 0.647 AUC. These results allow us to conclude that using the activity signal from a smartband, it is possible to distinguish between depressive states, providing a preliminary and automated tool to specialists for the diagnosis of depression almost in real time.
One of the principal conditions that affects oral health worldwide is dental caries, occurring in about 90% of the global population. This pathology has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused by a series of different demographic, dietary, among others. Based on this problem, in this research a demographic and dietary features analysis is performed for the classification of subjects according to their oral health status based on caries, according to the age group where the population belongs, using as feature selector a technique based on fast backward selection (FBS) approach for the development of three predictive models, one for each age range (group 1: 10–19; group 2: 20–59; group 3: 60 or more years old). As validation, a net reclassification improvement (NRI), AUC, ROC, and OR values are used to evaluate their classification accuracy. We analyzed 189 demographic and dietary features from National Health and Nutrition Examination Survey (NHANES) 2013–2014. Each model obtained statistically significant results for most features and narrow OR confidence intervals. Age group 2 obtained a mean NRI = −0.080 and AUC = 0.933; age group 3 obtained a mean NRI = −0.024 and AUC = 0.787; and age group 4 obtained a mean NRI = −0.129 and AUC = 0.735. Based on these results, it is concluded that these specific demographic and dietary features are significant determinants for estimating the oral health status in patients based on their likelihood of developing caries, and the age group could imply different risk factors for subjects.
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