Introduction:
Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality worldwide. The pre-immunosuppressed state along with other existing co-morbidities can influence the outcomes of COVID-19 in transplant patients
Material and Methods:
This was a single centre prospective cohort study done in kidney transplant recipients (KTRs), who underwent kidney transplantation (from December 2012 to November 2020), who were actively followed up at our centre and were diagnosed with COVID-19 disease between 1 April and 30 November 2020.
Results:
A total of 62 kidney-transplant recipients tested positive for COVID-19. Their median age was 39 (19–61). Males were predominantly infected (87.1%). Fever was the most common symptom (77.42%). Thirteen (20.9%) had mild form of disease, 32 (51.6%) had moderate form and 17 (27.4%) had severe disease. Based on initial symptom, 18 (29.03%) were given home treatment, 29 (46.7%) were treated in isolation wards and 15 (24.1%) were treated in intensive care unit. Decrease in the dose of immunosuppressant (anti-metabolites in 67.7%, calcineurin inhibitor in 22.5%) was predominantly carried out as the initial mode of treatment. Remdesivir in 64.5% and anticoagulant therapy in 54.84% were given as a modality of treatment. Mortality rate in our study was 14.5%.
Conclusions:
Patients of kidney transplant are at high risk of getting infected with COVID-19, due to their immunosuppressed state. Initial symptoms in KTRs with COVID-19 are similar to that of the general population. Mortality rate is comparatively higher in KTRs as compared to general population.
: Male sexual disorders remain taboo, particularly in a developing country like India. The affected census is under-depicted as of privacy issues, unawareness about the disease complex, a phobia about being affected, and many more counting on it, with advancing digitalization and many friendly social media platform, the affected individual logs onto the cybernet for perception, and here comes the role of content reliability.: In April 2022, we seek the most accountable social media platforms - with keywords of "Male Sexual Disorders", "Erectile Dysfunction", "Premature Ejaculation" and "Male sex Problems" using BuzzSumo, an online analytic tool. The collected content was evaluated by two urology residents on ground of European Association of Urology(EAU) Guidelines 2022, and for discrepancies, the final decision was established by a senior specialist.: Out of 191 included videos, 62.3% were videos uploaded by specialist and their mean duration was 7.2 minutes. 67.53% of uploaded videos explained general information (n=129, 67.53%) and provide information about diagnosis (28.7%) and treatment (78.01%), among which maximum videos favored medical management (97.9%). 158 inclusion videos (82.72%) were following EAU guidelines. In excluded videos, videos on alternative medicines shared maximum number (45.63%). Videos with animation and sound were more appealing based on views and likes, although the contribution of animated videos was rather less in number (25.65%). : The content with delusive information, small size samples, and individual opinion are having more luring appeasement. so, this study firms its ground by stressing verity of content and need for scrutiny by medical community.
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