Background: Recently, numerous studies have associated polymorphisms in 11beta-hydroxysteroid dehydrogenase type 1 (HSD11β1) gene and T2DM risk. However, there is still a lack in the published literature evaluating the association between HSD11β1gene polymorphism and the risk of T2DM. Objective: The Aim of the study was to assess the association of HSD11β1gene polymorphism (rs846910) with Type 2 diabetes mellitus (T2DM) in a sample of the Egyptian population. Patients and methods: Our study was conducted on 100 subjects; their mean age was 50.26 ± 9.1 years old. They were selected from Diabetes Outpatient Clinics of our institution for 6 months in the period from June 2019 to December 2019. They were divided into two groups: 60 type 2 diabetic obese patients with BMI > 25 kg/m 2 (Group I) and 40 age-and sex-matched controls (Group II). Results: There was no statistically significant difference between cases and controls in terms of HSD11β1 polymorphism (rs846910). The regression analysis showed that the HSD11β1 polymorphism did not significantly increase the risk of diabetes mellitus (DM). Detection of HSD11β1 gene polymorphism in the study showed that homozygous GG genotype was more prevalent than GA genotype. However, there was no significant difference between GG and GA in terms of fasting and postprandial sugar and in terms of lipid profile. Conclusion:The present study showed no significant association between HSD11β1 polymorphism (rs846910) and T2DM. Moreover, the HSD11β1polymorphism (rs846910) is not correlated with glycemic status or lipid profile.
EPCRC (Energy Pipeline Cooperative Research Centre in Australia) has developed a software package called EPDECOM to calculate the decompression wave speed of carbon dioxide mixtures containing impurities. The present report summarizes findings from the evaluation of the beta version of EPDECOM. The evaluation was based on the results of testing the 43 mixture compositions of CO2 binaries and the anthropogenic CO2+impuries used in the ALT-1-2 project.
The Pipeline Research Council International, Inc. found that Scandpower has software that is capable of predicting the transient response of a pipeline segment transporting either conventional or enriched dense phase natural gas mixtures when subjected to a controlled blow down or an uncontrolled rupture event. Consequently PRCI expressed a desire to pursue an experimental work to provide the basis for evaluating the adequacy of the existing software and/or define further development if any. NOVA Research and Technology Corporation (NRTC) was awarded a contract to perform the experimental work and compare results with prediction by the OLGA 2000 software. The existing NPS 2 stainless steel decompression tube test rig at TCPL Gas Dynamic Test Facility (GDTF) in Didsbury, Alberta, Canada, has been expanded specifically for this project. The initial length of 30 meters was extended to 172 meters in order to simulate a longer length to diameter (L/D) ratio. Two sets of tests were conducted: one to simulate pipeline rupture and another to simulate controlled blowdown. Rupture was simulated by a rupture disc located at one end of the tube, while blowdown was affected by a typical blowdown stack and a reduce-bore ball valve. The test scope included three gas mixtures (conventional, medium rich and rich) and three initial pressures: 10, 14 and 20 MPa.
There are three (3) documented Cathodic Protection (CP) criteria included in the NACE standards. The appropriate use of these are often debated and sometimes thought to be conservative in dry soils and possibly insufficient in some wet soil conditions. The need exists to evaluate the risks of an improperly installed and/or maintained CP system. The criteria for cathodic protection have been the subject of various research projects conducted for the Pipeline Research Council International, Inc. (PRCI) over a number of years. The programs have responded to the need to establish whether the present criteria are adequate or inadequate, and under what conditions, and whether the specific requirements for protection may depend upon the particular soil environment. The results of this study provide a comprehensive overview of the technical literature and the laboratory studies that formed the basis for this work. The results of this work include the first systematic study of the criteria as installed in the field. Field studies were initiated in 1984 with a multiyear (thru 1994) plan and objective of verifying the requirements for protection in a variety of natural environments, some of which were studied in the earlier laboratory research. Part I: Results of the research.Part II: Applications to the study, the limitations, methods of determining requirements of the pipeline, and the measurements needed to implement the results (60 figures and 56 tables).Part III: Study data (100 pages of charts and tables)
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